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Nurr1 agonist 8 (compound 111) is a Nurr1 agonist with an EC50 value of 0.09 μM.

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Nurr1 agonist 8 Chemical Structure

Nurr1 agonist 8 Chemical Structure

CAS No. : 360778-55-8

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Nurr1 agonist 8 Related Antibodies

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Description

Nurr1 agonist 8 (compound 111) is a Nurr1 agonist with an EC50 value of 0.09 μM[1].

Molecular Weight

297.13

Formula

C14H10Cl2O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC(OCC2=CC=C(C=C2Cl)Cl)=CC=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (420.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3655 mL 16.8277 mL 33.6553 mL
5 mM 0.6731 mL 3.3655 mL 6.7311 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3655 mL 16.8277 mL 33.6553 mL 84.1383 mL
5 mM 0.6731 mL 3.3655 mL 6.7311 mL 16.8277 mL
10 mM 0.3366 mL 1.6828 mL 3.3655 mL 8.4138 mL
15 mM 0.2244 mL 1.1218 mL 2.2437 mL 5.6092 mL
20 mM 0.1683 mL 0.8414 mL 1.6828 mL 4.2069 mL
25 mM 0.1346 mL 0.6731 mL 1.3462 mL 3.3655 mL
30 mM 0.1122 mL 0.5609 mL 1.1218 mL 2.8046 mL
40 mM 0.0841 mL 0.4207 mL 0.8414 mL 2.1035 mL
50 mM 0.0673 mL 0.3366 mL 0.6731 mL 1.6828 mL
60 mM 0.0561 mL 0.2805 mL 0.5609 mL 1.4023 mL
80 mM 0.0421 mL 0.2103 mL 0.4207 mL 1.0517 mL
100 mM 0.0337 mL 0.1683 mL 0.3366 mL 0.8414 mL
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Nurr1 agonist 8 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nurr1 agonist 8360778-55-8OthersNurr1FAM fragmentfatty acid metaboliteInhibitorinhibitorinhibit

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