2. Anti-infection
  3. Bacterial
  4. Octenidine

Octenidine is a potent antibacterial agent, possessing activity against multidrug-resistant Gram-negative pathogens. Octenidine can inhibit the expression of biofilm genes and destroy the formation of biofilms.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Octenidine dihydrochloride) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Octenidine Chemical Structure

Octenidine Chemical Structure

CAS No. : 71251-02-0

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Octenidine Related Antibodies

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Description

Octenidine is a potent antibacterial agent, possessing activity against multidrug-resistant Gram-negative pathogens. Octenidine can inhibit the expression of biofilm genes and destroy the formation of biofilms[1][3].

In Vitro

Octenidine has antimicrobial activity against multidrug-resistant Gram-negative pathogens[1].

Escherichia coli Pseudomonas aeruginosa
WT CTX-M-1 CTX-M-15 NDM-1 VIM-15 WT PER-1 VEB-1 OprD VIM-2
MIC (mg/L) 0.5 2.5 1.2 5 2.5 10 40 40 40 40

Octenidine (0-20 h) retardants P. aeruginosa growth in prolonged exposure condition[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Octenidine Related Antibodies
In Vivo

Octenidine reduces bacterial counts on mice wounds and inhibit meticillin-resistant Staphylococcus aureus (MRSA)[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice (a six-millimetre punch full-thickness wound was inoculated with MRSA suspension)[3]
Dosage:
Administration: Administrated once 24 hours post-wounding
Result: Accelerated healing and reduced by >3.6 log cfu/g bacterial counts on the wounds relative to the PBS-treated control.
Exhibited lower burden of the inflammatory cells, more mature collagen fibres and well-defined epithelialisation.
Inhibited the expression of MRSA and its biofilm genes by nearly 100%.
Clinical Trial
Molecular Weight

550.90

Formula

C36H62N4
CAS No.
SMILES

CCCCCCCC/N=C1C=CN(CCCCCCCCCCN(C=C/2)C=CC2=N/CCCCCCCC)C=C/1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Octenidine Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Octenidine71251-02-0Bacterialantibacterialmultidrug-resistantGram-negativeMRSAbiofilmInhibitorinhibitorinhibit

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