2. Oligonucleotides
  3. CpG ODNs
  4. ODN 1982 sodium

ODN 1982 sodium is a unmethylated oligodeoxyribonucleotide (ODN) with no CpG motif, and can be used to prepare DNA vaccines. ODN 1982 sodium inhibits R-848 signaling. ODN 1982 sequence: 5’-tccaggacttctctcaggtt-3’.

For research use only. We do not sell to patients.

DNA, d(P-thio)(T-C-C-A-G-G-A-C-T-T-C-T-C-T-C-A-G-G-T-T), sodium salt

ODN 1982 sodium Chemical Structure

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Based on 1 publication(s) in Google Scholar

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Description

ODN 1982 sodium is a unmethylated oligodeoxyribonucleotide (ODN) with no CpG motif, and can be used to prepare DNA vaccines. ODN 1982 sodium inhibits R-848 signaling. ODN 1982 sequence: 5’-tccaggacttctctcaggtt-3’[1][2].

Molecular Weight

6823.90

Appearance

Solid

Color

White to off-white

SMILES

[ODN 1982 (sodium)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (14.65 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.1465 mL 0.7327 mL 1.4654 mL
5 mM 0.0293 mL 0.1465 mL 0.2931 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.1465 mL 0.7327 mL 1.4654 mL 3.6636 mL
5 mM 0.0293 mL 0.1465 mL 0.2931 mL 0.7327 mL
10 mM 0.0147 mL 0.0733 mL 0.1465 mL 0.3664 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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ODN 1982 sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ODN 1982ODN1982ODN-1982OthersR-848 signalingHEK293LoxoribineIL-12p40TNFDNA vaccinesInhibitorinhibitorinhibit

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