2. Apoptosis
  3. Apoptosis
  4. Odoroside A

Odoroside A is an active ingredient extracted from the leaves of Nerium oleander Linn. Odoroside A has anti-cancer activity. Odoroside A could induce apoptosis and cell cycle arrest through ROS/p53 signaling pathway, leading to the tumor cell death.

For research use only. We do not sell to patients.

Odoroside A Chemical Structure

Odoroside A Chemical Structure

CAS No. : 12738-19-1

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1 mg USD 240 In-stock
5 mg USD 650 In-stock
10 mg USD 950 In-stock
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Based on 1 publication(s) in Google Scholar

Odoroside A Related Antibodies

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Description

Odoroside A is an active ingredient extracted from the leaves of Nerium oleander Linn. Odoroside A has anti-cancer activity. Odoroside A could induce apoptosis and cell cycle arrest through ROS/p53 signaling pathway, leading to the tumor cell death[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 316 μM
Compound: 6
Viability of human A549 cells by MTT assay after 24 hrs
Viability of human A549 cells by MTT assay after 24 hrs
[PMID: 17595134]
A549 IC50
0.2 μM
Compound: 6
Inhibition of induction of ICAM1 expression in human A549 cells in presence of IL1-alpha after 1 hr
Inhibition of induction of ICAM1 expression in human A549 cells in presence of IL1-alpha after 1 hr
[PMID: 17595134]
A549 IC50
0.48 μM
Compound: 6
Inhibition of induction of ICAM1 expression in human A549 cells in presence of TNFalpha after 1 hr
Inhibition of induction of ICAM1 expression in human A549 cells in presence of TNFalpha after 1 hr
[PMID: 17595134]
Molecular Weight

518.68

Formula

C30H46O7
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@@]([C@@]1(CC2)C)(CC[C@]1([H])C(CO3)=CC3=O)[C@@](CC[C@]4([H])C[C@H]5O[C@H](O[C@@H]6C)C[C@H]([C@H]6O)OC)([H])[C@@]2([H])[C@]4(CC5)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (192.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9280 mL 9.6399 mL 19.2797 mL
5 mM 0.3856 mL 1.9280 mL 3.8559 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9280 mL 9.6399 mL 19.2797 mL 48.1993 mL
5 mM 0.3856 mL 1.9280 mL 3.8559 mL 9.6399 mL
10 mM 0.1928 mL 0.9640 mL 1.9280 mL 4.8199 mL
15 mM 0.1285 mL 0.6427 mL 1.2853 mL 3.2133 mL
20 mM 0.0964 mL 0.4820 mL 0.9640 mL 2.4100 mL
25 mM 0.0771 mL 0.3856 mL 0.7712 mL 1.9280 mL
30 mM 0.0643 mL 0.3213 mL 0.6427 mL 1.6066 mL
40 mM 0.0482 mL 0.2410 mL 0.4820 mL 1.2050 mL
50 mM 0.0386 mL 0.1928 mL 0.3856 mL 0.9640 mL
60 mM 0.0321 mL 0.1607 mL 0.3213 mL 0.8033 mL
80 mM 0.0241 mL 0.1205 mL 0.2410 mL 0.6025 mL
100 mM 0.0193 mL 0.0964 mL 0.1928 mL 0.4820 mL
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Odoroside A Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Odoroside A12738-19-1Apoptosisanti-cancercellcyclearrestcolorectalcarcinomaInhibitorinhibitorinhibit

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