2. Neuronal Signaling
  3. OGT
  4. OGT-IN-1

OGT-IN-1 (Compound 5) is a potent OGT inhibitor. OGT-IN-1 inhibits sOGT and ncOGT with IC50s of 27 and 10 μM, respectively.

For research use only. We do not sell to patients.

OGT-IN-1 Chemical Structure

OGT-IN-1 Chemical Structure

CAS No. : 371215-02-0

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5 mg USD 30 In-stock
10 mg USD 48 In-stock
25 mg USD 96 In-stock
50 mg USD 153 In-stock
100 mg USD 245 In-stock
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Based on 1 publication(s) in Google Scholar

OGT-IN-1 Related Antibodies

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Description

OGT-IN-1 (Compound 5) is a potent OGT inhibitor. OGT-IN-1 inhibits sOGT and ncOGT with IC50s of 27 and 10 μM, respectively[1].

Molecular Weight

289.67

Formula

C14H8ClNO4
CAS No.
SMILES

O=C(N1C(OC2=CC=C(Cl)C=C12)=O)OC3=CC=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (172.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4522 mL 17.2610 mL 34.5220 mL
5 mM 0.6904 mL 3.4522 mL 6.9044 mL
View the Complete Stock Solution Preparation Table

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Purity & Documentation
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Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4522 mL 17.2610 mL 34.5220 mL 86.3051 mL
5 mM 0.6904 mL 3.4522 mL 6.9044 mL 17.2610 mL
10 mM 0.3452 mL 1.7261 mL 3.4522 mL 8.6305 mL
15 mM 0.2301 mL 1.1507 mL 2.3015 mL 5.7537 mL
20 mM 0.1726 mL 0.8631 mL 1.7261 mL 4.3153 mL
25 mM 0.1381 mL 0.6904 mL 1.3809 mL 3.4522 mL
30 mM 0.1151 mL 0.5754 mL 1.1507 mL 2.8768 mL
40 mM 0.0863 mL 0.4315 mL 0.8631 mL 2.1576 mL
50 mM 0.0690 mL 0.3452 mL 0.6904 mL 1.7261 mL
60 mM 0.0575 mL 0.2877 mL 0.5754 mL 1.4384 mL
80 mM 0.0432 mL 0.2158 mL 0.4315 mL 1.0788 mL
100 mM 0.0345 mL 0.1726 mL 0.3452 mL 0.8631 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

OGT-IN-1371215-02-0OGTO-linked N-acetylglucosaminyltransferaseO-GlcNAc transferaseInhibitorinhibitorinhibit

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