2. GPCR/G Protein
  3. LPL Receptor
  4. ONO-0740556

ONO-0740556 is a potent Gi-coupled human lysophosphatidic acid receptor 1 (LPA1) agonist with an EC50 value of 0.26 nM.

For research use only. We do not sell to patients.

ONO-0740556 Chemical Structure

ONO-0740556 Chemical Structure

CAS No. : 2250210-69-4

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5 mg USD 780 In-stock
10 mg USD 1250 In-stock
25 mg USD 2500 In-stock
50 mg USD 4050 In-stock
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Based on 1 publication(s) in Google Scholar

ONO-0740556 Related Antibodies

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Description

ONO-0740556 is a potent Gi-coupled human lysophosphatidic acid receptor 1 (LPA1) agonist with an EC50 value of 0.26 nM[1].

Molecular Weight

415.46

Formula

C20H34NO6P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=P(O)(O)OC[C@@H](CO)NC(CCCCC1=C(C=CC=C1)CCCCCC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 75 mg/mL (180.52 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4070 mL 12.0349 mL 24.0697 mL
5 mM 0.4814 mL 2.4070 mL 4.8139 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.67%

COA (246 KB) HNMR (205 KB) LCMS (92 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4070 mL 12.0349 mL 24.0697 mL 60.1743 mL
5 mM 0.4814 mL 2.4070 mL 4.8139 mL 12.0349 mL
10 mM 0.2407 mL 1.2035 mL 2.4070 mL 6.0174 mL
15 mM 0.1605 mL 0.8023 mL 1.6046 mL 4.0116 mL
20 mM 0.1203 mL 0.6017 mL 1.2035 mL 3.0087 mL
25 mM 0.0963 mL 0.4814 mL 0.9628 mL 2.4070 mL
30 mM 0.0802 mL 0.4012 mL 0.8023 mL 2.0058 mL
40 mM 0.0602 mL 0.3009 mL 0.6017 mL 1.5044 mL
50 mM 0.0481 mL 0.2407 mL 0.4814 mL 1.2035 mL
60 mM 0.0401 mL 0.2006 mL 0.4012 mL 1.0029 mL
80 mM 0.0301 mL 0.1504 mL 0.3009 mL 0.7522 mL
100 mM 0.0241 mL 0.1203 mL 0.2407 mL 0.6017 mL
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ONO-0740556 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ONO-07405562250210-69-4ONO0740556ONO 0740556LPL ReceptorLysophospholipid ReceptorLPA1human lysophosphatidic acid receptor 1Inhibitorinhibitorinhibit

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