2. GPCR/G Protein Immunology/Inflammation Anti-infection
  3. CCR HIV
  4. Ophiobolin C

Ophiobolin C inhibits CCR5 binding to the envelop protein gp120 and CD4, which is responsible for mediating the entry of HIV-1 into cells. Ophiobolin C is also cytotoxic to chronic lymphocytic leukemia cells.

For research use only. We do not sell to patients.

Ophiobolin C Chemical Structure

Ophiobolin C Chemical Structure

CAS No. : 19022-51-6

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Ophiobolin C Related Antibodies

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Description

Ophiobolin C inhibits CCR5 binding to the envelop protein gp120 and CD4, which is responsible for mediating the entry of HIV-1 into cells[1]. Ophiobolin C is also cytotoxic to chronic lymphocytic leukemia cells[2].

IC50 & Target

CCR5

 

HIV-1

 

Molecular Weight

386.57

Formula

C25H38O3
CAS No.
SMILES

O=C/C1=C/C[C@]([C@@H]([C@@H](C)CC/C=C(C)\C)CC2)([H])[C@@]2(C)C[C@@]([C@](C)(O)C3)([H])[C@]1([H])C3=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Ophiobolin C Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ophiobolin C19022-51-6Zizanin ACCRHIVCC chemokine receptorHuman immunodeficiency virusInhibitorinhibitorinhibit

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