Oxyphenonium bromide

Name: Oxyphenonium bromide
Brand: MedChemExpress
SKU: HY-B1719A
Rating: 4.5 (1 reviews)

Cat. No.: HY-B1719A Purity: 99.39%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Oxyphenonium bromide is an antiacetylcholine compound. Oxyphenonium bromide is an antagonist of mAChR. Oxyphenonium bromide protects against the bronchial obstructive effects.

For research use only. We do not sell to patients.

Oxyphenonium bromide Chemical Structure

CAS No. : 50-10-2

Size	Price	Stock	Quantity
10 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Oxyphenonium bromide is an antiacetylcholine compound. Oxyphenonium bromide is an antagonist of mAChR. Oxyphenonium bromide protects against the bronchial obstructive effects^[1]^[2]^[3].

Molecular Weight

428.40

Formula

C₂₁H₃₄BrNO₃

CAS No.

50-10-2

Appearance

Solid

Color

White to off-white

SMILES

O=C(OCC[N+](CC)(CC)C)C(O)(C1CCCCC1)C2=CC=CC=C2.[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 125 mg/mL (291.78 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.3343 mL	11.6713 mL	23.3427 mL
5 mM	0.4669 mL	2.3343 mL	4.6685 mL
10 mM	0.2334 mL	1.1671 mL	2.3343 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.39%

Select Batch:

Data Sheet (272 KB) SDS (251 KB)

COA (249 KB) HNMR (256 KB) LCMS (89 KB)

Handling Instructions (2659 KB)

References

[1]. Funasaki N, et al. Quantitative estimation of the bitter taste intensity of oxyphenonium bromide reduced by cyclodextrins from electromotive force measurements. Anal Chem. 1999 May 1;71(9):1733-6. [Content Brief]

[2]. Koëter GH, et al. Protective effect of oral oxyphenonium bromide, terbutaline and theophylline against the bronchial obstructive effects of inhaled histamine, acetylcholine and propranolol. Eur J Clin Pharmacol. 1984;26(4):435-41. [Content Brief]

[3]. Eglen RM, et al. Competitive and non-competitive antagonism exhibited by 'selective' antagonists at atrial and ileal muscarinic receptor subtypes. Br J Pharmacol. 1987 Apr;90(4):701-7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.3343 mL	11.6713 mL	23.3427 mL	58.3567 mL
	5 mM	0.4669 mL	2.3343 mL	4.6685 mL	11.6713 mL
	10 mM	0.2334 mL	1.1671 mL	2.3343 mL	5.8357 mL
	15 mM	0.1556 mL	0.7781 mL	1.5562 mL	3.8904 mL
	20 mM	0.1167 mL	0.5836 mL	1.1671 mL	2.9178 mL
	25 mM	0.0934 mL	0.4669 mL	0.9337 mL	2.3343 mL
	30 mM	0.0778 mL	0.3890 mL	0.7781 mL	1.9452 mL
	40 mM	0.0584 mL	0.2918 mL	0.5836 mL	1.4589 mL
	50 mM	0.0467 mL	0.2334 mL	0.4669 mL	1.1671 mL
	60 mM	0.0389 mL	0.1945 mL	0.3890 mL	0.9726 mL
	80 mM	0.0292 mL	0.1459 mL	0.2918 mL	0.7295 mL
	100 mM	0.0233 mL	0.1167 mL	0.2334 mL	0.5836 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.