2. Peptides
  3. Peptide and Derivatives
  4. Inhibitors and Substrates
  5. Oxytocin antiparallel dimer

Oxytocin antiparallel dimer is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin.

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Oxytocin antiparallel dimer Chemical Structure

Oxytocin antiparallel dimer Chemical Structure

CAS No. : 20054-93-7

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Based on 1 publication(s) in Google Scholar

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Oxytocin antiparallel dimer Related Antibodies

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Description

Oxytocin antiparallel dimer is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin[1][2].

In Vitro

The parallel and antiparallel homo/hetero bis-cystine dimers of oxytocin and deamino-oxytocin show biological activities ranged from 0.2% to 6% that of oxytocin[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Oxytocin antiparallel dimer Related Antibodies
In Vivo

Oxytocin dimer (iv; single dose) shows acute toxicity (LD50=43 mg/kg) is less than that of oxytocin (LD50=25 mg/kg) in rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

2014.37

Formula

C86H132N24O24S4
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

Sequence 1:CYIQNCPLG-NH2;Sequence 2:CYIQNCPLG-NH2 (Disulfide bridge:Chain1 Cys1 to Chain2 Cys6;Chain1 Cys6 to Chain2 Cys1)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (24.82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4964 mL 2.4822 mL 4.9643 mL
5 mM 0.0993 mL 0.4964 mL 0.9929 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.4964 mL 2.4822 mL 4.9643 mL 12.4108 mL
5 mM 0.0993 mL 0.4964 mL 0.9929 mL 2.4822 mL
10 mM 0.0496 mL 0.2482 mL 0.4964 mL 1.2411 mL
15 mM 0.0331 mL 0.1655 mL 0.3310 mL 0.8274 mL
20 mM 0.0248 mL 0.1241 mL 0.2482 mL 0.6205 mL
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Oxytocin antiparallel dimer Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Oxytocin antiparallel dimer20054-93-7OthersInhibitorinhibitorinhibit

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