2. Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. Androgen Receptor Drug Metabolite
  4. p,p'-DDE (Standard)

p,p'-DDE (Standard) is the analytical standard of p,p'-DDE. This product is intended for research and analytical applications. p,p'-DDE (4,4'-DDE) is the major and persistent metabolite of DDT. p,p'-DDE is a orally active androgen receptor antagonist with an IC50 of 5 μM and a Ki of 3.5 μM. p,p'-DDE can affect the development and function of the male reproductive system. Additionally, high serum concentrations of p,p'-DDE may be a risk factor for type 2 diabetes in women.

For research use only. We do not sell to patients.

p,p'-DDE (Standard) Chemical Structure

p,p'-DDE (Standard) Chemical Structure

CAS No. : 72-55-9

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p,p'-DDE (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

p,p'-DDE (Standard)72-55-9Androgen ReceptorDrug MetabolitetranscriptionalmetaboliteantiandrogenicdevelopmentaleffectsinvivoandInhibitorinhibitorinhibit

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