2. Reference Standards
  3. Metabolism Standards
  4. Drug Metabolite Standards

Drug Metabolite Standards

A drug metabolite is a byproduct of the body breaking down, or “metabolizing” a drug into a different substance. Most drugs undergo chemical alteration by various bodily systems as a way to create compounds that are more easily excreted from the body. Drug metabolism can produce metabolites with physicochemical and pharmacological properties that differ substantially from those of the parent drug, and consequently have important implications for both drug safety and efficacy.

Drug Metabolite Standards (217):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-138253R
    2′,2′-Difluorodeoxyuridine (Standard) 114248-23-6
    2′,2′-Difluorodeoxyuridine (Standard) is the analytical standard of 2′,2′-Difluorodeoxyuridine. This product is intended for research and analytical applications. 2′,2′-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2′,2′-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro.
    2′,2′-Difluorodeoxyuridine (Standard)
  • HY-107856R
    5-Fluorouridine (Standard) 316-46-1
    5-Fluorouridine (Standard) is the analytical standard of 5-Fluorouridine. This product is intended for research and analytical applications. 5-Fluorouridine, a metabolite of 5-fluorouracil (HY-90006), is a potent ribozyme self-cleavage inhibitor. 5-Fluorouridine incorporates into both total and poly A RNA and has antiproliferative activity. 5-Fluorouridine induces apoptosis.
    5-Fluorouridine (Standard)
  • HY-N7143R
    Monobutyl phthalate (Standard) 131-70-4
    Monobutyl phthalate (Standard) is the analytical standard of Monobutyl phthalate. This product is intended for research and analytical applications. Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant.
    Monobutyl phthalate (Standard)
  • HY-W001080R
    3,4-Dihydroxybenzeneacetic acid (Standard) 102-32-9
    3,4-Dihydroxybenzeneacetic acid (Standard) is the analytical standard of 3,4-Dihydroxybenzeneacetic acid. This product is intended for research and analytical applications. 3,4-Dihydroxybenzeneacetic acid is the main neuronal metabolite of dopamine.
    3,4-Dihydroxybenzeneacetic acid (Standard)
  • HY-N0384R
    Homovanillic acid (Standard) 306-08-1
    Homovanillic acid (Standard) is the analytical standard of Homovanillic acid. This product is intended for research and analytical applications. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.
    Homovanillic acid (Standard)
  • HY-B1348R
    Dimethadione (Standard) 695-53-4
    Dimethadione (Standard)
  • HY-133624R
    1,1,3-Tribromoacetone (Standard) 3475-39-6
    1,1,3-Tribromoacetone (Standard)
  • HY-B1103R
    Hydroxyhexamide (Standard) 3168-01-2
    Hydroxyhexamide (Standard)
  • HY-12778R
    Ivabradine metabolite N-Demethyl Ivabradine (hydrochloride) (Standard) 1246638-08-3
    Ivabradine metabolite N-Demethyl Ivabradine (hydrochloride) (Standard) is the analytical standard of Ivabradine metabolite N-Demethyl Ivabradine (hydrochloride). This product is intended for research and analytical applications. 0
    Ivabradine metabolite N-Demethyl Ivabradine (hydrochloride) (Standard)
  • HY-133779R
    Gefitinib impurity 5 (Standard) 199327-61-2
    Gefitinib impurity 5 (Standard) is the analytical standard of Gefitinib impurity 5. This product is intended for research and analytical applications. Gefitinib impurity 5 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity.
    Gefitinib impurity 5 (Standard)
  • HY-N3059R
    Pinostilbene (Standard) 42438-89-1
    Pinostilbene (Standard) is the analytical standard of Pinostilbene. This product is intended for research and analytical applications. Pinostilbene (trans-Pinostilbene) is a major metabolite of Pterostilbene. Pinostilbene exhibits inhibitory effects on colon cancer cells.
    Pinostilbene (Standard)
  • HY-W008449R
    1-Methylxanthine (Standard) 6136-37-4
    1-Methylxanthine (Standard) is the analytical standard of 1-Methylxanthine. This product is intended for research and analytical applications. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells.
    1-Methylxanthine (Standard)
  • HY-W019726R
    Dehydro Nifedipine (Standard) 67035-22-7
    Dehydro Nifedipine (Standard) is the analytical standard of Dehydro Nifedipine. This product is intended for research and analytical applications. Dehydro nifedipine (BAY-b 4759) is a metabolite of Nifedipine (HY-B0284). Nifedipine (BAY-a-1040) is a potent calcium channel blocker and an agent of choice for cardiac insufficiencies.
    Dehydro Nifedipine (Standard)
  • HY-N3995R
    5β-Dihydrocortisol (Standard) 1482-50-4
    D-Psicose (Standard) is the analytical standard of D-Psicose. This product is intended for research and analytical applications. D-Psicose is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    5β-Dihydrocortisol (Standard)
  • HY-W394903R
    GS-829845 (Standard) 1257705-09-1
    Isatin (Standard) is the analytical standard of Isatin. This product is intended for research and analytical applications. Isatin (Indoline-2,3-dione) is a potent inhibitor of monoamine oxidase (MAO) with an IC50 of 3 μM. Also binds to central benzodiazepine receptors (IC50 against clonazepam, 123 μM). Also acts as an antagonist of both atrial natriuretic peptide stimulated and nitric oxide-stimulated guanylate cyclase activity. Shows effect on the serotonergic system.
    GS-829845 (Standard)
  • HY-112226R
    VRT-043198 (Standard) 244133-31-1
    VRT-043198 (Standard)
  • HY-Z0075R
    (Z)2S,4R-Sacubitril (Standard)
    (Z)2S,4R-Sacubitril (Standard)
  • HY-111278R
    Pyocyanin (Standard) 85-66-5
    Pyocyanin (Standard)
  • HY-101406R
    Thyroxine sulfate (Standard) 77074-49-8
    Thyroxine sulfate (Standard)
  • HY-N7513R
    Homovanillyl alcohol (Standard) 2380-78-1
    Orphenadrine (hydrochloride) (Standard) is the analytical standard of Orphenadrine (hydrochloride). This product is intended for research and analytical applications. Orphenadrine hydrochloride is an orally active and non-competitive NMDA receptor antagonist (crosses the blood-brain barrier) with a Ki of 6.0 μM. Orphenadrine hydrochloride relieves stiffness, pain and discomfort due to muscle strains, sprains or other injuries. Orphenadrine hydrochloride is also used to relieve tremors associated with parkinson's disease. Orphenadrine citrate has good neuroprotective properties, can be used in studies of neurodegenerative diseases.
    Homovanillyl alcohol (Standard)