2. Cytoskeleton
  3. Dynamin
  4. P110 heptapeptide

P110 heptapeptide, a peptide inhibitor of Drp1-Fis1 interaction, reduces pathology in numerous models of neurodegeneration, ischemia, and sepsis without blocking the physiological functions of Drp1.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

P110 heptapeptide Chemical Structure

P110 heptapeptide Chemical Structure

CAS No. : 1411976-18-5

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1 mg USD 100 In-stock
5 mg USD 250 In-stock
10 mg USD 400 In-stock
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Based on 1 publication(s) in Google Scholar

P110 heptapeptide Related Antibodies

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Description

P110 heptapeptide, a peptide inhibitor of Drp1-Fis1 interaction, reduces pathology in numerous models of neurodegeneration, ischemia, and sepsis without blocking the physiological functions of Drp1[1].

Molecular Weight

756.85

Formula

C32H56N10O11
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Asp-Leu-Leu-Pro-Arg-Gly-Ser
Sequence Shortening

DLLPRGS
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (66.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3213 mL 6.6063 mL 13.2127 mL
5 mM 0.2643 mL 1.3213 mL 2.6425 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3213 mL 6.6063 mL 13.2127 mL 33.0316 mL
5 mM 0.2643 mL 1.3213 mL 2.6425 mL 6.6063 mL
10 mM 0.1321 mL 0.6606 mL 1.3213 mL 3.3032 mL
15 mM 0.0881 mL 0.4404 mL 0.8808 mL 2.2021 mL
20 mM 0.0661 mL 0.3303 mL 0.6606 mL 1.6516 mL
25 mM 0.0529 mL 0.2643 mL 0.5285 mL 1.3213 mL
30 mM 0.0440 mL 0.2202 mL 0.4404 mL 1.1011 mL
40 mM 0.0330 mL 0.1652 mL 0.3303 mL 0.8258 mL
50 mM 0.0264 mL 0.1321 mL 0.2643 mL 0.6606 mL
60 mM 0.0220 mL 0.1101 mL 0.2202 mL 0.5505 mL
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P110 heptapeptide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

P110 heptapeptide1411976-18-5DynaminHuntington’s diseaseamyotrophic lateral sclerosisALSAlzheimer’s diseaseParkinson’s diseasescrapiecardiac ischemiastrokeinflammatory bowel diseasesepsisInhibitorinhibitorinhibit

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