1. MAPK/ERK Pathway
  2. p38 MAPK
  3. p38α inhibitor 4

p38α inhibitor 4 (compound 10) is a selective and allosteric p38α inhibitor with an IC50 value of 1.2 μM. p38α inhibitor 4 exhibits no activity against p38β, p38γ, and p38δ.

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p38α inhibitor 4 Chemical Structure

p38α inhibitor 4 Chemical Structure

CAS No. : 1262406-08-5

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Description

p38α inhibitor 4 (compound 10) is a selective and allosteric p38α inhibitor with an IC50 value of 1.2 μM. p38α inhibitor 4 exhibits no activity against p38β, p38γ, and p38δ[1].

IC50 & Target[1]

p38α

1.2 μM (IC50)

Molecular Weight

347.22

Formula

C14H7F6N3O

CAS No.
SMILES

O=C1C=C(C(F)(F)F)C2=C(NN=C2C3=CC(C(F)(F)F)=CC=C3)N1

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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p38α inhibitor 4
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HY-14412
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