2. GPCR/G Protein Neuronal Signaling
  3. Melanocortin Receptor
  4. Palmitoyl tetrapeptide-20

Palmitoyl tetrapeptide-20  (Synonyms: PTP20)

Cat. No.: HY-P5247 Purity: 99.67%
SDS COA Handling Instructions

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Palmitoyl tetrapeptide-20 (PTP20) is a biomimetic peptide that is an agonist for α-MSH. Palmitoyl tetrapeptide-20 can protect follicular melanocytes and activate melanogenesis by enhancing catalase expression.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Palmitoyl tetrapeptide-20 Chemical Structure

Palmitoyl tetrapeptide-20 Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of Palmitoyl tetrapeptide-20:

Palmitoyl tetrapeptide-20 Related Antibodies

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Description

Palmitoyl tetrapeptide-20 (PTP20) is a biomimetic peptide that is an agonist for α-MSH. Palmitoyl tetrapeptide-20 can protect follicular melanocytes and activate melanogenesis by enhancing catalase expression[1].

Molecular Weight

739.00

Formula

C38H70N6O8
Appearance

Solid

Color

White to off-white

Sequence

{Pal}-Pro-Glu-Lys-Lys
Sequence Shortening

{Pal}-PEKK
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 28.57 mg/mL (38.66 mM; adjust pH to 4 with 1 M HCL; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3532 mL 6.7659 mL 13.5318 mL
5 mM 0.2706 mL 1.3532 mL 2.7064 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.67%

SDS (251 KB)

COA (253 KB) LCMS (90 KB) Elemental Analysis Report (112 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3532 mL 6.7659 mL 13.5318 mL 33.8295 mL
5 mM 0.2706 mL 1.3532 mL 2.7064 mL 6.7659 mL
10 mM 0.1353 mL 0.6766 mL 1.3532 mL 3.3829 mL
15 mM 0.0902 mL 0.4511 mL 0.9021 mL 2.2553 mL
20 mM 0.0677 mL 0.3383 mL 0.6766 mL 1.6915 mL
25 mM 0.0541 mL 0.2706 mL 0.5413 mL 1.3532 mL
30 mM 0.0451 mL 0.2255 mL 0.4511 mL 1.1276 mL
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Palmitoyl tetrapeptide-20 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Palmitoyl tetrapeptide-20PTP20Palmitoyl tetrapeptide20Palmitoyl tetrapeptide 20PTP 20PTP-20Melanocortin ReceptorMC Receptorα-MSHhair pigmentationhair greyingInhibitorinhibitorinhibit

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