Paricalcitol-d₆

Cat. No.: HY-76585 Purity: 99.64%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Paricalcitol-d₆ is the deuterium labeled Paricalcitol. Paricalcitol is a agent used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure[1].

For research use only. We do not sell to patients.

Paricalcitol-d<sub>6</sub> Chemical Structure

Paricalcitol-d₆ Chemical Structure

CAS No. : 2070009-67-3

Size	Price	Stock	Quantity
1 mg	USD 600	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 2880	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 4800	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

422.67

Formula

C₂₇H₃₈D₆O₃

CAS No.

2070009-67-3

Appearance

Solid

Color

White to off-white

SMILES

C[C@]([C@@H]([C@@H](/C=C/[C@@H](C(C([2H])([2H])[2H])(C([2H])([2H])[2H])O)C)C)CC1)(CCC/2)[C@@]1(C2=C\C=C3C[C@H](C[C@@H](C/3)O)O)[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (236.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.3659 mL	11.8296 mL	23.6591 mL
5 mM	0.4732 mL	2.3659 mL	4.7318 mL
10 mM	0.2366 mL	1.1830 mL	2.3659 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.64%

Select Batch:

Data Sheet (275 KB) SDS (252 KB)

COA (253 KB) LCMS (267 KB)

Handling Instructions (2659 KB)

References

[1]. Martinez-Moreno JM, et al. In vascular smooth muscle cells paricalcitol prevents phosphate-induced Wnt/beta-catenin activation. Am J Physiol Renal Physiol. 2012 Aug 8. [Content Brief]

[2]. Ari E, Kedrah AE, Alahdab Y, Bulut G, Eren Z, Baytekin O, Odabasi D. Antioxidant and renoprotective effects of paricalcitol on experimental contrast-induced nephropathy model. Br J Radiol. 2012 Aug;85(1016):1038-43. [Content Brief]

[3]. Meems LM, Cannon MV, Mahmud H, Voors AA, van Gilst WH, Silljé HH, Ruifrok WP, de Boer RA. The vitamin D receptor activator paricalcitol prevents fibrosis and diastolic dysfunction in a murine model of pressure overload. J Steroid Biochem Mol Biol. 2012 Jul 16;132(3-5):282-289. [Content Brief]

[4]. Blanco-García R, et al. Microalbuminuria, another use for paricalcitol? Our experience in advanced chronic kidney disease. Nefrologia. 2012 May 14;32(3):401-2. doi: 10.3265/Nefrologia.pre2012.Feb.11378. [Content Brief]

[5]. Piao SG, Song JC, Lim SW, Chung BH, Choi BS, Yang CW. Protective effect of paricalcitol on cyclosporine-induced renal injury in rats. Transplant Proc. 2012 Apr;44(3):642-5. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / DMSO	1 mM	2.3659 mL	11.8296 mL	23.6591 mL	59.1478 mL
	5 mM	0.4732 mL	2.3659 mL	4.7318 mL	11.8296 mL
	10 mM	0.2366 mL	1.1830 mL	2.3659 mL	5.9148 mL
	15 mM	0.1577 mL	0.7886 mL	1.5773 mL	3.9432 mL
	20 mM	0.1183 mL	0.5915 mL	1.1830 mL	2.9574 mL
	25 mM	0.0946 mL	0.4732 mL	0.9464 mL	2.3659 mL
	30 mM	0.0789 mL	0.3943 mL	0.7886 mL	1.9716 mL
	40 mM	0.0591 mL	0.2957 mL	0.5915 mL	1.4787 mL
	50 mM	0.0473 mL	0.2366 mL	0.4732 mL	1.1830 mL
	60 mM	0.0394 mL	0.1972 mL	0.3943 mL	0.9858 mL
	80 mM	0.0296 mL	0.1479 mL	0.2957 mL	0.7393 mL
	100 mM	0.0237 mL	0.1183 mL	0.2366 mL	0.5915 mL