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PARP1-IN-31 (compound 11f) is a phthalazinone-based compound, an anti-lung adenocarcinoma compound with inhibitory activity against PARP-1 (IC50 value of 97 nM), inducing apoptosis and inhibiting cell proliferation in lung cancer cell lines.

For research use only. We do not sell to patients.

PARP1-IN-31 Chemical Structure

PARP1-IN-31 Chemical Structure

CAS No. : 684234-60-4

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10 mg USD 75 In-stock
25 mg USD 150 In-stock
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Based on 1 publication(s) in Google Scholar

PARP1-IN-31 Related Antibodies

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Description

PARP1-IN-31 (compound 11f) is a phthalazinone-based compound, an anti-lung adenocarcinoma compound with inhibitory activity against PARP-1 (IC50 value of 97 nM), inducing apoptosis and inhibiting cell proliferation in lung cancer cell lines.

Molecular Weight

407.82

Formula

C22H15ClFN3O2
CAS No.
SMILES

O=C(NC1=CC=C(F)C=C1)CN(N=C(C2=CC=C(Cl)C=C2)C3=C4C=CC=C3)C4=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (306.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4521 mL 12.2603 mL 24.5206 mL
5 mM 0.4904 mL 2.4521 mL 4.9041 mL
View the Complete Stock Solution Preparation Table

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This equation is commonly abbreviated as: C1V1 = C2V2

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Purity & Documentation
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Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4521 mL 12.2603 mL 24.5206 mL 61.3016 mL
5 mM 0.4904 mL 2.4521 mL 4.9041 mL 12.2603 mL
10 mM 0.2452 mL 1.2260 mL 2.4521 mL 6.1302 mL
15 mM 0.1635 mL 0.8174 mL 1.6347 mL 4.0868 mL
20 mM 0.1226 mL 0.6130 mL 1.2260 mL 3.0651 mL
25 mM 0.0981 mL 0.4904 mL 0.9808 mL 2.4521 mL
30 mM 0.0817 mL 0.4087 mL 0.8174 mL 2.0434 mL
40 mM 0.0613 mL 0.3065 mL 0.6130 mL 1.5325 mL
50 mM 0.0490 mL 0.2452 mL 0.4904 mL 1.2260 mL
60 mM 0.0409 mL 0.2043 mL 0.4087 mL 1.0217 mL
80 mM 0.0307 mL 0.1533 mL 0.3065 mL 0.7663 mL
100 mM 0.0245 mL 0.1226 mL 0.2452 mL 0.6130 mL
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PARP1-IN-31 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PARP1-IN-31684234-60-4OthersInhibitorinhibitorinhibit

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PARP1-IN-31
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HY-164713
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