2. Cell Cycle/DNA Damage
  3. TOPK
  4. PBK-IN-9

PBK-IN-9 (compound 1160) is a potent PDZ binding kinase (PBK) inhibitor.

For research use only. We do not sell to patients.

PBK-IN-9 Chemical Structure

PBK-IN-9 Chemical Structure

CAS No. : 1338540-55-8

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Based on 1 publication(s) in Google Scholar

PBK-IN-9 Related Antibodies

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Description

PBK-IN-9 (compound 1160) is a potent PDZ binding kinase (PBK) inhibitor[1].

Molecular Weight

350.43

Formula

C20H18N2O2S
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1NC2=C(C(C3=CC=C([C@@H](C)CN)C=C3)=C(O)C=C2)C4=C1SC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (28.54 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8536 mL 14.2682 mL 28.5364 mL
5 mM 0.5707 mL 2.8536 mL 5.7073 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8536 mL 14.2682 mL 28.5364 mL 71.3409 mL
5 mM 0.5707 mL 2.8536 mL 5.7073 mL 14.2682 mL
10 mM 0.2854 mL 1.4268 mL 2.8536 mL 7.1341 mL
15 mM 0.1902 mL 0.9512 mL 1.9024 mL 4.7561 mL
20 mM 0.1427 mL 0.7134 mL 1.4268 mL 3.5670 mL
25 mM 0.1141 mL 0.5707 mL 1.1415 mL 2.8536 mL
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PBK-IN-9 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PBK-IN-91338540-55-8TOPKT-LAK cell-originated protein kinaseInhibitorinhibitorinhibit

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