2. Metabolic Enzyme/Protease
  3. PCSK9
  4. PCSK9-IN-15

PCSK9-IN-15 (compound 5) is a potent inhibitor of proprotein convertase subtilisin/kexin 9 (PCSK9, KD <200 nM). PCSK9 is involved in cholesterol metabolism and regulates levels of low-density lipoprotein cholesterol (LDL-C) in the blood. PCSK9- in -15 can be used to study cholesterol-lowering and dyslipidemia.

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PCSK9-IN-15 Chemical Structure

PCSK9-IN-15 Chemical Structure

CAS No. : 2455423-94-4

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PCSK9-IN-15 Related Antibodies

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Description

PCSK9-IN-15 (compound 5) is a potent inhibitor of proprotein convertase subtilisin/kexin 9 (PCSK9, KD <200 nM). PCSK9 is involved in cholesterol metabolism and regulates levels of low-density lipoprotein cholesterol (LDL-C) in the blood. PCSK9- in -15 can be used to study cholesterol-lowering and dyslipidemia[1].

IC50 & Target

PCSK9[1]
Molecular Weight

472.63

Formula

C22H28N6O2S2
CAS No.
SMILES

O=C(N1CCC(CC1)O)C2=CC=C(N=C(S3)NC[C@@H](C)CNC4=NC=C(SC)C=N4)C3=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PCSK9-IN-15 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PCSK9-IN-152455423-94-4PCSK9Proprotein convertase subtilisin/kexin type 9proprotein convertase subtilisin/kexin 9cholesterol metabolismlow-density lipoprotein cholesterolcholesterol-loweringdyslipidemiaInhibitorinhibitorinhibit

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PCSK9-IN-15
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HY-153451
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