1. Protein Tyrosine Kinase/RTK
  2. FGFR
  3. Pemigatinib (Standard)

Pemigatinib (Standard) 

Cat. No.: HY-109099R Purity: ≥98%
Handling Instructions

Pemigatinib (Standard) is the analytical standard of Pemigatinib. This product is intended for research and analytical applications. Pemigatinib (INCB054828) is an orally active, selective FGFR inhibitor with IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively. Pemigatinib has the potential for cholangiocarcinoma.

For research use only. We do not sell to patients.

Pemigatinib (Standard) Chemical Structure

Pemigatinib (Standard) Chemical Structure

CAS No. : 1513857-77-6

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Description
Molecular Weight

487.50

Formula

C24H27F2N5O4

CAS No.
SMILES

CCN(C(N(C(C(F)=C(OC)C=C1OC)=C1F)C2)=O)C(C2=CN3)=C4C3=NC(CN5CCOCC5)=C4

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Pemigatinib (Standard) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Pemigatinib (Standard)
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HY-109099R
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