1. Stem Cell/Wnt
  2. Wnt
  3. Pen-N3

Pen-N3 is a PDZ peptide. Pen-N3 inhibits Wnt/b-catenin signaling by recognizing dishevelled protein.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Pen-N3 Chemical Structure

Pen-N3 Chemical Structure

Size Price Stock Quantity
5 mg USD 210 In-stock
10 mg USD 335 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

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  • Customer Review

Description

Pen-N3 is a PDZ peptide. Pen-N3 inhibits Wnt/b-catenin signaling by recognizing dishevelled protein[1].

Molecular Weight

1071.22

Formula

C51H78N10O15

Appearance

Solid

Color

White to off-white

Sequence

Glu-Ile-Val-Leu-Trp-Ser-Asp-Ile-Pro

Sequence Shortening

EIVLWSDIP

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (93.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9335 mL 4.6676 mL 9.3352 mL
5 mM 0.1867 mL 0.9335 mL 1.8670 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9335 mL 4.6676 mL 9.3352 mL 23.3379 mL
5 mM 0.1867 mL 0.9335 mL 1.8670 mL 4.6676 mL
10 mM 0.0934 mL 0.4668 mL 0.9335 mL 2.3338 mL
15 mM 0.0622 mL 0.3112 mL 0.6223 mL 1.5559 mL
20 mM 0.0467 mL 0.2334 mL 0.4668 mL 1.1669 mL
25 mM 0.0373 mL 0.1867 mL 0.3734 mL 0.9335 mL
30 mM 0.0311 mL 0.1556 mL 0.3112 mL 0.7779 mL
40 mM 0.0233 mL 0.1167 mL 0.2334 mL 0.5834 mL
50 mM 0.0187 mL 0.0934 mL 0.1867 mL 0.4668 mL
60 mM 0.0156 mL 0.0778 mL 0.1556 mL 0.3890 mL
80 mM 0.0117 mL 0.0583 mL 0.1167 mL 0.2917 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Pen-N3
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HY-P10164
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