1. Peptides
  2. Peptide and Derivatives
  3. Peptides for Drug Delivery
  4. Cell-penetrating Peptides
  5. Penetratin

Penetratin is a peptide derived from the amphiphilic Drosophila Antennapedia homeodomain.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Penetratin Chemical Structure

Penetratin Chemical Structure

CAS No. : 940866-75-1

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1 mg USD 100 In-stock
5 mg USD 260 In-stock
10 mg USD 420 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Penetratin is a peptide derived from the amphiphilic Drosophila Antennapedia homeodomain[1].

Molecular Weight

2360.83

Formula

C108H174N36O22S

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Gly-Gly

Sequence Shortening

RQIKIWFQNRRMKWKKGG

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (42.36 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4236 mL 2.1179 mL 4.2358 mL
5 mM 0.0847 mL 0.4236 mL 0.8472 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.4236 mL 2.1179 mL 4.2358 mL 10.5895 mL
5 mM 0.0847 mL 0.4236 mL 0.8472 mL 2.1179 mL
10 mM 0.0424 mL 0.2118 mL 0.4236 mL 1.0589 mL
15 mM 0.0282 mL 0.1412 mL 0.2824 mL 0.7060 mL
20 mM 0.0212 mL 0.1059 mL 0.2118 mL 0.5295 mL
25 mM 0.0169 mL 0.0847 mL 0.1694 mL 0.4236 mL
30 mM 0.0141 mL 0.0706 mL 0.1412 mL 0.3530 mL
40 mM 0.0106 mL 0.0529 mL 0.1059 mL 0.2647 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Penetratin
Cat. No.:
HY-P2529
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