2. NF-κB
  3. NF-κB
  4. Penicisteck acid F

Penicisteck acid F (Compound 2) is a Marine derived tanzanic acid derivative that is a NF-κB inhibitor. Penicisteck acid F inhibits osteoclast expression by decreasing RANKL-induced IκBα degradation, NF-κB p65 nuclear translocation, NFATc1 activation and nuclear translocation, and related mRNA expression. Penicisteck acid F can be used in osteoporosis research.

For research use only. We do not sell to patients.

Penicisteck acid F Chemical Structure

Penicisteck acid F Chemical Structure

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Penicisteck acid F Related Antibodies

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Description

Penicisteck acid F (Compound 2) is a Marine derived tanzanic acid derivative that is a NF-κB inhibitor. Penicisteck acid F inhibits osteoclast expression by decreasing RANKL-induced IκBα degradation, NF-κB p65 nuclear translocation, NFATc1 activation and nuclear translocation, and related mRNA expression. Penicisteck acid F can be used in osteoporosis research[1].

Molecular Weight

288.38

Formula

C18H24O3
SMILES

C[C@@H](C[C@H](C1=C(C(C)=CC=C1)/C=C/C=C/C(O)=O)C)CO
Structure Classification
Initial Source

Penicillium steckii
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Penicisteck acid F Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Penicisteck acid FNF-κBNuclear factor-κBNuclear factor-kappaBOsteoclastogenesisOsteoporosisInhibitorinhibitorinhibit

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