Peroxy Orange 1  (Synonyms: PO1)

Peroxy Orange 1 (PO1) is a new H₂O₂ specific probe that can bind to green fluorescent highly reactive oxygen species (hROS) probe APF. Peroxy Orange 1 is also a living cell dye^[1][2].

521.41

C₃₂H₃₂BNO₅

1199576-10-7

Solid

Off-white to pink

O=C1OC2(C3=CC4=C5N(CCC4)CCCC5=C3OC6=C2C=CC(B7OC(C)(C)C(C)(C)O7)=C6)C8=C1C=CC=C8

Room temperature in continental US; may vary elsewhere.

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

• [1]. Dickinson BC, et al. A palette of fluorescent probes with varying emission colors for imaging hydrogen peroxide signaling in living cells. J Am Chem Soc. 2010 Apr 28;132(16):5906-15.  [Content Brief]

  [2]. Moloney JN, et al. Subcellular localization of the FLT3-ITD oncogene plays a significant role in the production of NOX- and p22phox-derived reactive oxygen species in acute myeloid leukemia. Leuk Res. 2017 Jan;52:34-42.  [Content Brief]