1. Immunology/Inflammation Apoptosis
  2. Complement System Apoptosis
  3. Pexelizumab

Pexelizumab  (Synonyms: h5G1. 1-SC)

Cat. No.: HY-P99886

Pexelizumab (h5G1. 1-SC) is a humanized scFv monoclonal antibody directed against the C5 complement component. Pexelizumab inhibits apoptosis and leukocyte infiltration. Pexelizumab can be used for the research of cerebral IR injury and myocardial infarction.

For research use only. We do not sell to patients.

CAS No. : 219685-93-5

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Description

Pexelizumab (h5G1. 1-SC) is a humanized scFv monoclonal antibody directed against the C5 complement component. Pexelizumab inhibits apoptosis and leukocyte infiltration. Pexelizumab can be used for the research of cerebral IR injury and myocardial infarction[1][2].

In Vitro

Pexelizumab (h5G1. 1-SC) inhibits 5G1.1 mAb binding with an IC50 of 1.5 nM[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS No.
SMILES

[Pexelizumab]

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Format
  • scFv-kappa-heavy
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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