2. MAPK/ERK Pathway
  3. MAP4K
  4. PF-06260933 hydrochloride

PF-06260933 hydrochloride is the hydrochloride form of PF-06260933 (HY-19562). PF-06260933 hydrochloride is an orally active and highly selective inhibitor of MAP4K4 with IC50s of 3.7 and 160 nM for kinase and cell, respectively.

For research use only. We do not sell to patients.

PF-06260933 hydrochloride Chemical Structure

PF-06260933 hydrochloride Chemical Structure

CAS No. : 1883548-86-4

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PF-06260933 hydrochloride Related Antibodies

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MAP4K2/GCK MAP4K3/GLK MAP4K4/HGK MAP4K5/KHS1 MAP4K6/MINK1 MAP4K7/TNIK MAP4K1/HPK1

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Description

PF-06260933 hydrochloride is the hydrochloride form of PF-06260933 (HY-19562). PF-06260933 hydrochloride is an orally active and highly selective inhibitor of MAP4K4 with IC50s of 3.7 and 160 nM for kinase and cell, respectively[1].

Molecular Weight

369.68

Formula

C16H15Cl3N4
CAS No.
SMILES

NC1=C(C2=CC=C(Cl)C=C2)C=C(C(C=N3)=CC=C3N)C=N1.Cl.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PF-06260933 hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PF-062609331883548-86-4PF06260933PF 06260933MAP4KMAPK Kinase Kinase KinasehydrochlorideMAP4K4 inhibitororally activekinaseInhibitorinhibitorinhibit

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PF-06260933 hydrochloride
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HY-19562A
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