2. Neuronal Signaling
  3. Beta-secretase
  4. PF-06663195

PF-06663195 is a β-secretase (BACE1) inhibitor, with BACE1 CFA and BACE1 WCA IC50 values of 53 and 15 nM, respectively. PF-06663195 can be used for Alzheimer's disease research.

For research use only. We do not sell to patients.

PF-06663195 Chemical Structure

PF-06663195 Chemical Structure

CAS No. : 1621585-22-5

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PF-06663195 Related Antibodies

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Description

PF-06663195 is a β-secretase (BACE1) inhibitor, with BACE1 CFA and BACE1 WCA IC50 values of 53 and 15 nM, respectively. PF-06663195 can be used for Alzheimer's disease research[1].

Molecular Weight

397.41

Formula

C18H18F3N3O2S
CAS No.
SMILES

FC[C@@H]1[C@@]2([H])[C@](N=C(S1)N)(C3=C(C=C(C=C3)F)F)CO[C@@H](C4=CC(C)=NO4)C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PF-06663195 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PF-066631951621585-22-5PF06663195PF 06663195Beta-secretaseBACEβ-SecretaseAlzheimer's diseaseBACE1 CFAInhibitorinhibitorinhibit

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