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  4. PG-11047 tetrahydrochloride

PG-11047 tetrahydrochloride  (Synonyms: CGC-11047 tetrahydrochloride)

Cat. No.: HY-16394 Purity: ≥98.0%
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PG-11047 (CGC-11047), a polyamine analogue, is a nonfunctional competitor of the natural polyamine spermine. PG-11047 has broad spectrum anticancer activities.

For research use only. We do not sell to patients.

PG-11047 tetrahydrochloride Chemical Structure

PG-11047 tetrahydrochloride Chemical Structure

CAS No. : 206991-64-2

Size Price Stock Quantity
5 mg USD 397 In-stock
10 mg USD 636 In-stock
25 mg USD 1336 In-stock
50 mg USD 2138 In-stock
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Based on 1 publication(s) in Google Scholar

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PG-11047 tetrahydrochloride Related Antibodies

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Description

PG-11047 (CGC-11047), a polyamine analogue, is a nonfunctional competitor of the natural polyamine spermine. PG-11047 has broad spectrum anticancer activities[1][2].

Molecular Weight

402.27

Formula

C14H36Cl4N4
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

CCNCCCNC/C=C\CNCCCNCC.[H]Cl.[H]Cl.[H]Cl.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 30 mg/mL (74.58 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4859 mL 12.4295 mL 24.8589 mL
5 mM 0.4972 mL 2.4859 mL 4.9718 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.4859 mL 12.4295 mL 24.8589 mL 62.1473 mL
5 mM 0.4972 mL 2.4859 mL 4.9718 mL 12.4295 mL
10 mM 0.2486 mL 1.2429 mL 2.4859 mL 6.2147 mL
15 mM 0.1657 mL 0.8286 mL 1.6573 mL 4.1432 mL
20 mM 0.1243 mL 0.6215 mL 1.2429 mL 3.1074 mL
25 mM 0.0994 mL 0.4972 mL 0.9944 mL 2.4859 mL
30 mM 0.0829 mL 0.4143 mL 0.8286 mL 2.0716 mL
40 mM 0.0621 mL 0.3107 mL 0.6215 mL 1.5537 mL
50 mM 0.0497 mL 0.2486 mL 0.4972 mL 1.2429 mL
60 mM 0.0414 mL 0.2072 mL 0.4143 mL 1.0358 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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PG-11047 tetrahydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PG-11047 tetrahydrochloride206991-64-2CGC-11047 tetrahydrochlorideOtherspolyamine analoguebreast cancerlymphomaInhibitorinhibitorinhibit

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