1. GPCR/G Protein
  2. Vasopressin Receptor
  3. (Phe2,Orn8)-Oxytocin

(Phe2,Orn8)-Oxytocin is a selective V1 vasopressin agonist. (Phe2,Orn8)-Oxytocin induces a sustained contractility of rabbit epididymis with EC50 value of 280 nM.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

(Phe2,Orn8)-Oxytocin Chemical Structure

(Phe2,Orn8)-Oxytocin Chemical Structure

CAS No. : 2480-41-3

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Based on 1 publication(s) in Google Scholar

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Description

(Phe2,Orn8)-Oxytocin is a selective V1 vasopressin agonist. (Phe2,Orn8)-Oxytocin induces a sustained contractility of rabbit epididymis with EC50 value of 280 nM[1].

Molecular Weight

992.18

Formula

C42H65N13O11S2

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Cys-Phe-Ile-Gln-Asn-Cys-Pro-{Orn}-Gly-NH2 (Disulfide bridge: Cys1-Cys6)

Sequence Shortening

CFIQNCP-{Orn}-G-NH2 (Disulfide bridge: Cys1-Cys6)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (50.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0079 mL 5.0394 mL 10.0788 mL
5 mM 0.2016 mL 1.0079 mL 2.0158 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.0079 mL 5.0394 mL 10.0788 mL 25.1970 mL
5 mM 0.2016 mL 1.0079 mL 2.0158 mL 5.0394 mL
10 mM 0.1008 mL 0.5039 mL 1.0079 mL 2.5197 mL
15 mM 0.0672 mL 0.3360 mL 0.6719 mL 1.6798 mL
20 mM 0.0504 mL 0.2520 mL 0.5039 mL 1.2599 mL
25 mM 0.0403 mL 0.2016 mL 0.4032 mL 1.0079 mL
30 mM 0.0336 mL 0.1680 mL 0.3360 mL 0.8399 mL
40 mM 0.0252 mL 0.1260 mL 0.2520 mL 0.6299 mL
50 mM 0.0202 mL 0.1008 mL 0.2016 mL 0.5039 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(Phe2,Orn8)-Oxytocin
Cat. No.:
HY-P4678
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