2. PROTAC
  3. Ligands for E3 Ligase
  4. Phenyl-glutarimide 4'-oxyacetic acid

Phenyl-glutarimide 4 ’-oxyacetic acid is a carboxylic acid-functionalized cerebellar ligand that can be used in the development of PROTAC deactivators. Phenyl-glutarimide 4 ’-oxyacetic acid binds to PROTAC has better hydrolytic stability and efficacy.

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Phenyl-glutarimide 4'-oxyacetic acid Chemical Structure

Phenyl-glutarimide 4'-oxyacetic acid Chemical Structure

CAS No. : 2782024-58-0

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Phenyl-glutarimide 4'-oxyacetic acid Related Antibodies

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View All Ligands for E3 Ligase Isoform Specific Products:

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von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1

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Description

Phenyl-glutarimide 4 ’-oxyacetic acid is a carboxylic acid-functionalized cerebellar ligand that can be used in the development of PROTAC deactivators. Phenyl-glutarimide 4 ’-oxyacetic acid binds to PROTAC has better hydrolytic stability and efficacy[1].

Molecular Weight

263.25

Formula

C13H13NO5
CAS No.
SMILES

O=C(COC1=CC=C(C2C(NC(CC2)=O)=O)C=C1)O
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Phenyl-glutarimide 4'-oxyacetic acid Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phenyl-glutarimide 4'-oxyacetic acid2782024-58-0Ligands for E3 LigaseE3 ligase-recruiting Moietycerebellar ligandPROTACPGInhibitorinhibitorinhibit

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