Ligands for E3 Ligase Inhibitors

von Hippel-Lindau (VHL)

MDM2

Cereblon

IAP

KLHDC2

Fbxo3

RNF4

DCAF11

DCAF1

UHRF1

Ligands for E3 Ligase Degraders, Inhibitors & Modulators

Product Name	von Hippel-Lindau (VHL)	MDM2	Cereblon	IAP	KLHDC2	Fbxo3	RNF4	DCAF11	DCAF1	UHRF1	Purity
Lenalidomide			Cereblon								99.95%
Pomalidomide			Cereblon								99.96%
Eragidomide			Cereblon								99.86%
VH032	VHL										99.64%
(S,R,S)-AHPC-Me hydrochloride	VHL										99.59%
(S,R,S)-AHPC monohydrochloride	VHL										99.83%
Golcadomide			Cereblon
(S,R,S)-AHPC	VHL										99.13%
Lenalidomide hemihydrate			Cereblon								99.67%
(S,R,S)-AHPC-Me	VHL										99.48%
ALV1			Cereblon
Lenalidomide-Br			Cereblon								99.86%
VH032-cyclopropane-F	VHL										99.92%
BC-1215						Fbxo3					99.93%
(S,S,S)-AHPC hydrochloride	VHL										99.42%
Lenalidomide-OH			Cereblon								99.48%
(S)-Thalidomide			Cereblon								99.65%
NV03										UHRF1	98.82%
Biotin-Thalidomide			Cereblon								99.65%
cIAP1 ligand 1				cIAP1							99.90%
VHL Ligand 8	VHL										98.04%
VL285	VHL										98.84%
Nutlin carboxylic acid		MDM2									98.63%
KB02-COOH			Cereblon								99.39%
(S,R,S)-AHPC-Boc	VHL
(S,R,S)-AHPC-Me dihydrochloride	VHL										99.84%
CCW16							RNF4				98.63%
CC-17369			Cereblon								98.13%
Lenalidomide-F			Cereblon
VH 101, thiol	VHL										98.66%
Cereblon inhibitor 1			Cereblon								99.19%
Pomalidomide-5-OH			Cereblon								99.46%
E3 ligase Ligand 23			Cereblon								99.71%
CRBN modulator-1			Cereblon								98.00%
2-Methoxyphenyl dihydrouracil			Cereblon
E3 ligase Ligand 18			Cereblon								99.22%
Thalidomide-piperazine hydrochloride			Cereblon								98.27%
VH032 thiol	VHL
Pomalidomide-6-OH			Cereblon								98.09%
(R)-Thalidomide			Cereblon								99.80%
Lenalidomide hydrochloride			Cereblon
(S,R,S)-AHPC TFA	VHL
Aster-A Ligand-3			Cereblon
E3 ligase Ligand 26			Cereblon
E3 ligase Ligand 42			Cereblon
E3 ligase Ligand 22			Cereblon
Pomalidomide-5-O-CH3			Cereblon
DA-PROTAC	VHL
(4R,5S)-Nutlin carboxylic acid		MDM2
PROTAC CRBN ligand-2			Cereblon
HOXB7 8–25		MDM2
E3 ligase Ligand 38			Cereblon
E3 ligase Ligand 37	VHL
E3 ligase Ligand 36	VHL
E3 ligase Ligand PG			Cereblon, IC₅₀: 2.191 μM
Bestatin-amido-Me				cIAP1
E3 ligase Ligand 31			Cereblon
Cyclopropane-(S,R,S)-AHPC	VHL
E3 ligase Ligand 44	VHL
E3 ligase Ligand 27	VHL
E3 ligase Ligand 25			Cereblon
(S)-Deoxy-thalidomide-Br			Cereblon
Acepromazine-OTs			Cereblon
E3 ligase Ligand 21			Cereblon
MV-1-NH-Me				cIAP1
CRBN ligand-11			Cereblon
MY-11B									DCAF1
E3 ligase Ligand 45	VHL
HL389			Cereblon
(3S)Lenalidomide-5-Br			Cereblon
OICR-8268-acrylic acid	VHL
N-Boc-SBP-0636457-OH				cIAP1
E3 ligase Ligand 33	VHL
(S,R,S)-AHPC dihydrochloride	VHL
E3 ligase Ligand 35	VHL
E3 ligase Ligand 43	VHL
E3 ligase Ligand 7								DCAF11
AS1411-C4-VH032		MDM2
cIAP1 ligand 2				cIAP1
L321			Cereblon
Pomalidomide-6-O-CH3			Cereblon
SJ6145					KLHDC2
Benzothiazole-CH2(NH-CO-CH2Cl)-CONH-CH2-Ph	VHL

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