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  4. Phenylquinone

Phenylquinone  (Synonyms: 2-Phenylbenzoquinone)

Cat. No.: HY-W275039 Purity: 97.26%
Data Sheet
SDS
COA
Handling Instructions Technical Support

Solubility

In Vivo Dissolution Calculator

Phenylquinone (2-Phenylbenzoquinone) causes pain and induces writhing in mice, and is often used in experiments to test the effectiveness of analgesics or agent that can suppress or relieve pain.

For research use only. We do not sell to patients.

Phenylquinone Chemical Structure

Phenylquinone Chemical Structure

CAS No. : 363-03-1

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 52 In-stock
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Solid
5 mg USD 50 In-stock
10 mg USD 70 In-stock
25 mg USD 120 In-stock
50 mg USD 165 In-stock
100 mg USD 245 In-stock
200 mg   Get quote  
500 mg   Get quote  

Get it by April 8 for select sizes. Order within 7 hrs 49 mins.

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Customer Review

Based on 1 publication(s) in Google Scholar

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  • Biological Activity

  • Purity & Documentation

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Description

Phenylquinone (2-Phenylbenzoquinone) causes pain and induces writhing in mice, and is often used in experiments to test the effectiveness of analgesics or agent that can suppress or relieve pain[1][2].

Molecular Weight

184.19

Formula

C12H8O2
CAS No.
Appearance

Solid

Color

Light yellow to brown

SMILES

C1=CC=C(C=C1)C2=CC(=O)C=CC2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (542.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4291 mL 27.1453 mL 54.2906 mL
5 mM 1.0858 mL 5.4291 mL 10.8581 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.5 mg/mL (13.57 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, PEG300/PEG400, Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Purity & Documentation

Purity: 97.26%

Data Sheet (274 KB) SDS (393 KB)

COA (251 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.4291 mL 27.1453 mL 54.2906 mL 135.7265 mL
5 mM 1.0858 mL 5.4291 mL 10.8581 mL 27.1453 mL
10 mM 0.5429 mL 2.7145 mL 5.4291 mL 13.5726 mL
15 mM 0.3619 mL 1.8097 mL 3.6194 mL 9.0484 mL
20 mM 0.2715 mL 1.3573 mL 2.7145 mL 6.7863 mL
25 mM 0.2172 mL 1.0858 mL 2.1716 mL 5.4291 mL
30 mM 0.1810 mL 0.9048 mL 1.8097 mL 4.5242 mL
40 mM 0.1357 mL 0.6786 mL 1.3573 mL 3.3932 mL
50 mM 0.1086 mL 0.5429 mL 1.0858 mL 2.7145 mL
60 mM 0.0905 mL 0.4524 mL 0.9048 mL 2.2621 mL
80 mM 0.0679 mL 0.3393 mL 0.6786 mL 1.6966 mL
100 mM 0.0543 mL 0.2715 mL 0.5429 mL 1.3573 mL
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Phenylquinone Related Classifications

Keywords:

Phenylquinone363-03-12-PhenylbenzoquinoneBiochemical Assay ReagentsInhibitorinhibitorinhibit

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