2. GPCR/G Protein
  3. GnRH Receptor
  4. Phoenixin-14

Phoenixin-14  (Synonyms: PNX-14)

Cat. No.: HY-P5762 Purity: 99.57%
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Phoenixin-14 (PNX-14) is one of the endogenous active isoform, and generates anxiolytic effect via the activation of the AHA GnRH system in mice. Phoenixin-14 inhibits ischemia/reperfusion-induced cytotoxicity in microglia.

For research use only. We do not sell to patients.

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Phoenixin-14 Chemical Structure

Phoenixin-14 Chemical Structure

CAS No. : 1415039-79-0

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1 mg USD 75 In-stock
5 mg USD 188 In-stock
10 mg USD 300 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Phoenixin-14 (PNX-14) is one of the endogenous active isoform, and generates anxiolytic effect via the activation of the AHA GnRH system in mice. Phoenixin-14 inhibits ischemia/reperfusion-induced cytotoxicity in microglia[1][2].

Molecular Weight

1583.78

Formula

C75H110N18O20
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Asp-Val-Gln-Pro-Pro-Gly-Leu-Lys-Val-Trp-Ser-Asp-Pro-Phe-NH2
Sequence Shortening

DVQPPGLKVWSDPF-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (63.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6314 mL 3.1570 mL 6.3140 mL
5 mM 0.1263 mL 0.6314 mL 1.2628 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6314 mL 3.1570 mL 6.3140 mL 15.7850 mL
5 mM 0.1263 mL 0.6314 mL 1.2628 mL 3.1570 mL
10 mM 0.0631 mL 0.3157 mL 0.6314 mL 1.5785 mL
15 mM 0.0421 mL 0.2105 mL 0.4209 mL 1.0523 mL
20 mM 0.0316 mL 0.1579 mL 0.3157 mL 0.7893 mL
25 mM 0.0253 mL 0.1263 mL 0.2526 mL 0.6314 mL
30 mM 0.0210 mL 0.1052 mL 0.2105 mL 0.5262 mL
40 mM 0.0158 mL 0.0789 mL 0.1579 mL 0.3946 mL
50 mM 0.0126 mL 0.0631 mL 0.1263 mL 0.3157 mL
60 mM 0.0105 mL 0.0526 mL 0.1052 mL 0.2631 mL
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Phoenixin-14 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phoenixin-141415039-79-0PNX-14Phoenixin14Phoenixin 14PNX14PNX 14GnRH ReceptorGonadotropin releasing hormone receptorGNRHRanxiolytic effectischemia/reperfusionmicrogliaInhibitorinhibitorinhibit

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