2. PI3K/Akt/mTOR
  3. PI3K mTOR
  4. PI3K/mTOR Inhibitor-14

PI3K/mTOR Inhibitor-14 (compound Y-2) is a potent PI3K and mTOR dual inhibitor with IC50s of 171.4 nM and 10.1 nM, respectively. PI3K/mTOR Inhibitor-14 has antitumor activities.

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PI3K/mTOR Inhibitor-14 Chemical Structure

PI3K/mTOR Inhibitor-14 Chemical Structure

CAS No. : 2919684-77-6

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PI3K/mTOR Inhibitor-14 Related Antibodies

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PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

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mTOR mTORC1 mTORC2

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Description

PI3K/mTOR Inhibitor-14 (compound Y-2) is a potent PI3K and mTOR dual inhibitor with IC50s of 171.4 nM and 10.1 nM, respectively. PI3K/mTOR Inhibitor-14 has antitumor activities[1].

IC50 & Target[1]

PI3K

171.4 nM (IC50)

mTOR

10.1 nM (IC50)

Molecular Weight

558.65

Formula

C28H30N8O3S
CAS No.
SMILES

O=C(NC1=CC=C(C2=NC(N3CCOCC3)=NC(C4=CC=C(CN5CCOCC5)S4)=N2)C=C1)NC6=CC=CN=C6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PI3K/mTOR Inhibitor-14 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PI3K/mTOR Inhibitor-142919684-77-6PI3KmTORPhosphoinositide 3-kinaseMammalian target of RapamycinInhibitorinhibitorinhibit

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