2. PI3K/Akt/mTOR
  3. PI3K mTOR
  4. PI3K/mTOR Inhibitor-5

PI3K/mTOR Inhibitor-5 (compound 19a) is a potent and dual PI3K and mTOR inhibitor, with IC50 values of 86.9 nM and 14.6 nM, respectively.

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PI3K/mTOR Inhibitor-5 Chemical Structure

PI3K/mTOR Inhibitor-5 Chemical Structure

CAS No. : 2456295-60-4

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PI3K/mTOR Inhibitor-5 Related Antibodies

Top Publications Citing Use of Products

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PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

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mTOR mTORC1 mTORC2

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Description

PI3K/mTOR Inhibitor-5 (compound 19a) is a potent and dual PI3K and mTOR inhibitor, with IC50 values of 86.9 nM and 14.6 nM, respectively[1].

IC50 & Target

IC50: 86.9 nM (PI3K), 14.6 nM (mTOR)[1]
Molecular Weight

612.73

Formula

C32H40N10O3
CAS No.
SMILES

O=C(N1CCC(N(C)C)CC1)C2=CC=C3N=C(NC4=CC=C(C5=NC(N6CCOCC6)=NC(N7CCOCC7)=N5)C=C4)NC3=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PI3K/mTOR Inhibitor-5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PI3K/mTOR Inhibitor-52456295-60-4PI3KmTORPhosphoinositide 3-kinaseMammalian target of RapamycinInhibitorinhibitorinhibit

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