2. PI3K/Akt/mTOR
  3. PI3K
  4. PI3Kα-IN-19

PI3Kα-IN-19 (Compound 1) is a PI3Kα inhibitor with a targeted binding site at the p110α catalytic subunit. PI3Kα is one of the most common dysregulated kinases used in cancer research.

For research use only. We do not sell to patients.

PI3Kα-IN-19 Chemical Structure

PI3Kα-IN-19 Chemical Structure

CAS No. : 885692-56-8

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PI3Kα-IN-19 Related Antibodies

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PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

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Description

PI3Kα-IN-19 (Compound 1) is a PI3Kα inhibitor with a targeted binding site at the p110α catalytic subunit. PI3Kα is one of the most common dysregulated kinases used in cancer research[1].

IC50 & Target

p110α

 

Molecular Weight

496.56

Formula

C28H28N6O3
CAS No.
SMILES

O=C(C1=NC(C#N)=CN1)NC2=CC=C(C(CC3)CCN3C(C4=C[N+]([O-])=CC=C4)=O)C=C2C5=CCCCC5
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PI3Kα-IN-19 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PI3Kα-IN-19885692-56-8PI3KPhosphoinositide 3-kinasePhosphoinositide 3-kinase alphaMolecular dynamics simulationInhibitorinhibitorinhibit

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