2. JAK/STAT Signaling
  3. Pim
  4. Pim-1 kinase inhibitor 5

Pim-1 kinase inhibitor 5 (Compound 4c) is a Pim-1 kinase inhibitor (IC50: 0.61 μM). Pim-1 kinase inhibitor 5 shows cytotoxicity against cancer cells, with IC50s of 6.95-20.19 μM for HepG2, MCF-7, PC3, and HCT-116 cells.

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Pim-1 kinase inhibitor 5 Chemical Structure

Pim-1 kinase inhibitor 5 Chemical Structure

CAS No. : 2928606-67-9

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Pim-1 kinase inhibitor 5 Related Antibodies

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Description

Pim-1 kinase inhibitor 5 (Compound 4c) is a Pim-1 kinase inhibitor (IC50: 0.61 μM). Pim-1 kinase inhibitor 5 shows cytotoxicity against cancer cells, with IC50s of 6.95-20.19 μM for HepG2, MCF-7, PC3, and HCT-116 cells[1].

Molecular Weight

406.26

Formula

C22H13Cl2N3O
CAS No.
SMILES

ClC(C(C1=CC(C2=CC=C(OC)C=C2)=NC(Cl)=C1C#N)=C3)=NC4=C3C=CC=C4
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Pim-1 kinase inhibitor 5 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pim-1 kinase inhibitor 52928606-67-9PimPim kinasesAnti-cancerHepG2MCF-7PC3HCT-116Inhibitorinhibitorinhibit

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