Pim Inhibitors

PIM1

PIM2

PIM3

Pim Inhibitors

Product Name	PIM1	PIM2	PIM3	Purity
AZD1208		PIM2		99.71%
CRT0066101 dihydrochloride		PIM2, IC₅₀: 135.7 nM		99.92%
PIM-447 dihydrochloride	PIM1	PIM2	PIM3	99.94%
AZD1897	PIM1, IC₅₀: <3 nM	PIM2, IC₅₀: <3 nM	PIM3, IC₅₀: <3 nM
Pim-1 kinase inhibitor 11	PIM1, IC₅₀: 0.18 μM
PIM-1/CK2-IN-2	PIM1
Pim1/AKK1-IN-1	PIM1			98.20%
Quercetagetin	PIM1, IC₅₀: 0.34 μM	PIM2, IC₅₀: 3.45 μM		99.94%
SMI-4a	PIM1, IC₅₀: 24 μM PIM1, Ki: 0.6 μM	PIM2, IC₅₀: 100 μM		99.63%
GDC-0339	PIM1	PIM2	PIM3	99.87%
PIM447	PIM1	PIM2	PIM3	99.78%
SMI-16a	PIM1	PIM2		≥98.0%
Uzansertib phosphate	PIM1, IC₅₀: 0.24 nM	PIM2, IC₅₀: 30 nM	PIM3, IC₅₀: 0.12 nM	99.39%
CK2/ERK8-IN-1	PIM1, Ki: 8.65 μM			≥99.0%
SEL24-B489	PIM1, Kd: 2 nM	PIM2, Kd: 2 nM	PIM3, Kd: 3 nM	99.02%
TCS PIM-1 1	PIM1, IC₅₀: 50 nM			98.01%
CRT0066101		PIM2, IC₅₀: 135.7 nM
PIM1-IN-1	PIM1, IC₅₀: 7 nM	PIM2, IC₅₀: 5530 nM	PIM3, IC₅₀: 70 nM	99.83%
HTH-01-091	PIM1, IC₅₀: 60.6 nM			98.64%
PIM1-IN-2	PIM1, Ki: 91 nM			≥99.0%
GNE-955	PIM1, Ki: 0.018 nM	PIM2, Ki: 0.11 nM	PIM3, Ki: 0.08 nM
Uzansertib	PIM1, IC₅₀: 0.24 nM	PIM2, IC₅₀: 30 nM	PIM3, IC₅₀: 0.12 nM
HS56	PIM1, Ki: 2.94 μM	PIM2, Ki: ＞100 μM	PIM3, Ki: 0.208 μM
CK2/PIM1-IN-1	PIM1, IC₅₀: 4.327 μM
CDK6/PIM1-IN-1	PIM1, IC₅₀: 88 nM	PIM2, IC₅₀: >10 μM	PIM3, IC₅₀: 92 nM
PIM1-IN-7	PIM1, IC₅₀: 0.67 μM
PIM1-IN-6	PIM1, IC₅₀: 0.60 μM
PIM1-IN-4	PIM1
Pim-1 kinase inhibitor 3	PIM1, IC₅₀: 35.13 nM
Multi-kinase-IN-6	PIM1, IC₅₀: 0.42 μM
PIM-1/HDAC-IN-1	PIM1, IC₅₀: 343.87 ± 1 nM
Pim-1 kinase inhibitor 9	PIM1, IC₅₀: 0.24 μM	PIM2, IC₅₀: 10.53 μM
PIM-IN-2		PIM2
CRT0066101 trihydrochloride		PIM2, IC₅₀: 135.7 nM
PIM3-IN-1 hydrochloride		PIM2	PIM3
PIM1-IN-3	PIM1
GSK-3β inhibitor 13	PIM1, IC₅₀: 0.38 μM
Pim-1/2 kinase inhibitor 2	PIM1, IC₅₀: 1.31 μM	PIM2, IC₅₀: 0.67 μM

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