2. JAK/STAT Signaling Apoptosis
  3. Pim Apoptosis
  4. PIM1-IN-3

PIM1-IN-3 (Compound HL8) is a potent inhibitor of PIM1. PIM1-IN-3 shows selective inhibition for the PIM-1 enzyme. PIM1-IN-3 induces apoptosis efficiently in Colo320 cells. PIM1-IN-3 has the potential for the research of cancer diseases.

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PIM1-IN-3 Chemical Structure

PIM1-IN-3 Chemical Structure

CAS No. : 2762767-56-4

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PIM1-IN-3 Related Antibodies

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Description

PIM1-IN-3 (Compound HL8) is a potent inhibitor of PIM1. PIM1-IN-3 shows selective inhibition for the PIM-1 enzyme. PIM1-IN-3 induces apoptosis efficiently in Colo320 cells. PIM1-IN-3 has the potential for the research of cancer diseases[1].

IC50 & Target

PIM1

 

Molecular Weight

529.43

Formula

C27H25BrN6O
CAS No.
SMILES

C/C(C1=CC=C(C=N1)CN2CCOCC2)=N\N=C(C3=C4C5=CC(Br)=CC=C5N3)/NC6=C4C=CC=C6
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PIM1-IN-3 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PIM1-IN-32762767-56-4PimApoptosisPim kinasesPIM1selectiveapoptosiscancerInhibitorinhibitorinhibit

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