2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. Piperidine-4-sulfonic acid

Piperidine-4-sulfonic acid is a potent GABA agonist with an IC50 of 0.034 μM for the inhibition of the binding of H-GABA.

For research use only. We do not sell to patients.

Piperidine-4-sulfonic acid Chemical Structure

Piperidine-4-sulfonic acid Chemical Structure

CAS No. : 72450-62-5

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10 mg USD 224 In-stock
25 mg USD 403 In-stock
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Piperidine-4-sulfonic acid Related Antibodies

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Description

Piperidine-4-sulfonic acid is a potent GABA agonist with an IC50 of 0.034 μM for the inhibition of the binding of H-GABA[1].

IC50 & Target

IC50: 0.034 μM (the binding of H-GABA)[1]
Molecular Weight

165.21

Formula

C5H11NO3S
CAS No.
Appearance

Solid

Color

Light brown to brown

SMILES

O=S(C1CCNCC1)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (605.29 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.0529 mL 30.2645 mL 60.5290 mL
5 mM 1.2106 mL 6.0529 mL 12.1058 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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C2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.0529 mL 30.2645 mL 60.5290 mL 151.3226 mL
5 mM 1.2106 mL 6.0529 mL 12.1058 mL 30.2645 mL
10 mM 0.6053 mL 3.0265 mL 6.0529 mL 15.1323 mL
15 mM 0.4035 mL 2.0176 mL 4.0353 mL 10.0882 mL
20 mM 0.3026 mL 1.5132 mL 3.0265 mL 7.5661 mL
25 mM 0.2421 mL 1.2106 mL 2.4212 mL 6.0529 mL
30 mM 0.2018 mL 1.0088 mL 2.0176 mL 5.0441 mL
40 mM 0.1513 mL 0.7566 mL 1.5132 mL 3.7831 mL
50 mM 0.1211 mL 0.6053 mL 1.2106 mL 3.0265 mL
60 mM 0.1009 mL 0.5044 mL 1.0088 mL 2.5220 mL
80 mM 0.0757 mL 0.3783 mL 0.7566 mL 1.8915 mL
100 mM 0.0605 mL 0.3026 mL 0.6053 mL 1.5132 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Piperidine-4-sulfonic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Piperidine-4-sulfonic acid72450-62-5GABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorInhibitorinhibitorinhibit

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