1. Cell Cycle/DNA Damage
  2. Polo-like Kinase (PLK)
  3. PLK4-IN-3

PLK4-IN-3 is a less active absolute stereochemistry of PLK4-IN-1. PLK4-IN-1 is a PLK4 inhibitor, with an IC50 of 0.65 μM.

For research use only. We do not sell to patients.

PLK4-IN-3 Chemical Structure

PLK4-IN-3 Chemical Structure

CAS No. : 1247001-86-0

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Description

PLK4-IN-3 is a less active absolute stereochemistry of PLK4-IN-1. PLK4-IN-1 is a PLK4 inhibitor, with an IC50 of 0.65 μM[1].

IC50 & Target[1]

PLK4

≤ 0.1 μM (IC50)

Molecular Weight

431.23

Formula

C18H14IN3O2

CAS No.
SMILES

O=C([C@@]12[C@H](C3=CC4=C(C=C3)C(I)=NN4)C1)NC5=C2C=C(OC)C=C5

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PLK4-IN-3
Cat. No.:
HY-134775A
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