2. Metabolic Enzyme/Protease
  3. Liposome
  4. PNI 132

PNI 132, an ionizable lipid derived from the patent WO2020252589A, is useful in the formulation of lipid nanoparticles.

For research use only. We do not sell to patients.

PNI 132 Chemical Structure

PNI 132 Chemical Structure

CAS No. : 2568616-81-7

Size Price Stock Quantity
5 mg USD 500 Get quote 3 - 5 weeks 3 - 5 weeks 2 - 4 weeks
10 mg USD 800 Get quote 3 - 5 weeks 3 - 5 weeks 2 - 4 weeks
25 mg USD 1600 Get quote 3 - 5 weeks 3 - 5 weeks 2 - 4 weeks
50 mg USD 2580 Get quote 3 - 5 weeks 3 - 5 weeks 2 - 4 weeks
100 mg USD 4150 Get quote 3 - 5 weeks 3 - 5 weeks 2 - 4 weeks
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PNI 132 Related Antibodies

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Description

PNI 132, an ionizable lipid derived from the patent WO2020252589A, is useful in the formulation of lipid nanoparticles.

Molecular Weight

908.43

Formula

C58H101NO6
CAS No.
Appearance

Liquid (Density: 0.98±0.1 g/cm3)

Color

Colorless to light yellow

SMILES

CC/C=C\CC1C(CCC1CC(OCC(OCCCCCCCC/C=C\C/C=C\CCCCC)COCCCCCCCC/C=C\C/C=C\CCCCC)=O)OC(C2CCN(CC2)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (110.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1008 mL 5.5040 mL 11.0080 mL
5 mM 0.2202 mL 1.1008 mL 2.2016 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 96.62%

COA (240 KB) HNMR (298 KB) RP-HPLC (229 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1008 mL 5.5040 mL 11.0080 mL 27.5200 mL
5 mM 0.2202 mL 1.1008 mL 2.2016 mL 5.5040 mL
10 mM 0.1101 mL 0.5504 mL 1.1008 mL 2.7520 mL
15 mM 0.0734 mL 0.3669 mL 0.7339 mL 1.8347 mL
20 mM 0.0550 mL 0.2752 mL 0.5504 mL 1.3760 mL
25 mM 0.0440 mL 0.2202 mL 0.4403 mL 1.1008 mL
30 mM 0.0367 mL 0.1835 mL 0.3669 mL 0.9173 mL
40 mM 0.0275 mL 0.1376 mL 0.2752 mL 0.6880 mL
50 mM 0.0220 mL 0.1101 mL 0.2202 mL 0.5504 mL
60 mM 0.0183 mL 0.0917 mL 0.1835 mL 0.4587 mL
80 mM 0.0138 mL 0.0688 mL 0.1376 mL 0.3440 mL
100 mM 0.0110 mL 0.0550 mL 0.1101 mL 0.2752 mL
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PNI 132 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PNI 1322568616-81-7PNI132PNI-132LiposomeInhibitorinhibitorinhibit

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