2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. Pomalidomide-C7-NH2 hydrochloride

Pomalidomide-C7-NH2 hydrochloride  (Synonyms: Pomalidomide 4'-alkylC7-amine hydrochloride)

Cat. No.: HY-131878 Purity: 98.98%
COA Handling Instructions

Molarity Calculator

Pomalidomide-C7-NH2 (Pomalidomide 4'-alkylC7-amine) hydrochloride is an E3 ligase ligand-linker conjugate. Pomalidomide-C7-NH2 hydrochloride can be used for the synthesis of PROTAC.

For research use only. We do not sell to patients.

Pomalidomide-C7-NH2 hydrochloride Chemical Structure

Pomalidomide-C7-NH2 hydrochloride Chemical Structure

CAS No. : 2446474-05-9

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5 mg USD 55 In-stock
10 mg USD 90 In-stock
25 mg USD 190 In-stock
50 mg USD 300 In-stock
100 mg USD 450 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Pomalidomide-C7-NH2 hydrochloride:

Pomalidomide-C7-NH2 hydrochloride Related Antibodies

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Description

Pomalidomide-C7-NH2 (Pomalidomide 4'-alkylC7-amine) hydrochloride is an E3 ligase ligand-linker conjugate. Pomalidomide-C7-NH2 hydrochloride can be used for the synthesis of PROTAC[1][2].

Molecular Weight

422.91

Formula

C20H27ClN4O4
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCCCCCN)=O.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (295.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3646 mL 11.8228 mL 23.6457 mL
5 mM 0.4729 mL 2.3646 mL 4.7291 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.98%

COA (248 KB) HNMR (272 KB) LCMS (95 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3646 mL 11.8228 mL 23.6457 mL 59.1142 mL
5 mM 0.4729 mL 2.3646 mL 4.7291 mL 11.8228 mL
10 mM 0.2365 mL 1.1823 mL 2.3646 mL 5.9114 mL
15 mM 0.1576 mL 0.7882 mL 1.5764 mL 3.9409 mL
20 mM 0.1182 mL 0.5911 mL 1.1823 mL 2.9557 mL
25 mM 0.0946 mL 0.4729 mL 0.9458 mL 2.3646 mL
30 mM 0.0788 mL 0.3941 mL 0.7882 mL 1.9705 mL
40 mM 0.0591 mL 0.2956 mL 0.5911 mL 1.4779 mL
50 mM 0.0473 mL 0.2365 mL 0.4729 mL 1.1823 mL
60 mM 0.0394 mL 0.1970 mL 0.3941 mL 0.9852 mL
80 mM 0.0296 mL 0.1478 mL 0.2956 mL 0.7389 mL
100 mM 0.0236 mL 0.1182 mL 0.2365 mL 0.5911 mL
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Pomalidomide-C7-NH2 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pomalidomide-C7-NH22446474-05-9Pomalidomide 4'-alkylC7-amineE3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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