2. Anti-infection
  3. Fungal
  4. Posaconazole-d4

Posaconazole-d4  (Synonyms: SCH 56592-d4)

Cat. No.: HY-17373S1 Purity: 99.04%
SDS COA Handling Instructions

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Posaconazole-d4 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity[1].

For research use only. We do not sell to patients.

Posaconazole-d<sub>4</sub> Chemical Structure

Posaconazole-d4 Chemical Structure

CAS No. : 1133712-26-1

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Based on 1 publication(s) in Google Scholar

Other Forms of Posaconazole-d4:

Posaconazole-d4 Related Antibodies

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Description

Posaconazole-d4 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity[1].

Molecular Weight

704.80

Formula

C37H38D4F2N8O4
CAS No.
Unlabeled CAS

171228-49-2
Appearance

Solid

Color

White to off-white

SMILES

FC1=CC=C([C@@]2(CN3C=NC=N3)C[C@H](COC4=CC=C(N5CCN(C6=C([2H])C([2H])=C(N7C=NN([C@@H](CC)[C@H](C)O)C7=O)C([2H])=C6[2H])CC5)C=C4)CO2)C(F)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 18.75 mg/mL (26.60 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4188 mL 7.0942 mL 14.1884 mL
5 mM 0.2838 mL 1.4188 mL 2.8377 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.04%

SDS (252 KB)

COA (248 KB) LCMS (100 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4188 mL 7.0942 mL 14.1884 mL 35.4711 mL
5 mM 0.2838 mL 1.4188 mL 2.8377 mL 7.0942 mL
10 mM 0.1419 mL 0.7094 mL 1.4188 mL 3.5471 mL
15 mM 0.0946 mL 0.4729 mL 0.9459 mL 2.3647 mL
20 mM 0.0709 mL 0.3547 mL 0.7094 mL 1.7736 mL
25 mM 0.0568 mL 0.2838 mL 0.5675 mL 1.4188 mL
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Posaconazole-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Posaconazole-d41133712-26-1SCH 56592-d4FungalInhibitorinhibitorinhibit

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