1. Immunology/Inflammation
  2. Kallikrein
  3. PPACK II

PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (PPACK II diTFA) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

PPACK II Chemical Structure

PPACK II Chemical Structure

CAS No. : 74392-49-7

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Description

PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor[1].

In Vitro

PPACK II (0.62-50 μg/mL) significantly inhibits B-type natriuretic peptide (BNP) proteolysis[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

501.02

Formula

C25H33ClN6O3

CAS No.
SMILES

N=C(N)NCCC[C@@H](C(CCl)=O)NC([C@@H](NC([C@H](N)CC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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PPACK II Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PPACK II
Cat. No.:
HY-122543A
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