Propargyl-PEG1-NHS ester

Cat. No.: HY-126513 Purity: ≥95.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Propargyl-PEG1-NHS ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-PEG1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

For research use only. We do not sell to patients.

Propargyl-PEG1-NHS ester Chemical Structure

CAS No. : 1174157-65-3

Size	Price	Stock	Quantity
25 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 130	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
Customer Review

Description

IC₅₀ & Target

Non-cleavable Linker

Molecular Weight

225.20

Formula

C₁₀H₁₁NO₅

CAS No.

1174157-65-3

Appearance

Liquid (Density: 1.32±0.1 g/cm³)

Color

Colorless to light yellow

SMILES

O=C(ON1C(CCC1=O)=O)CCOCC#C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (444.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.4405 mL	22.2025 mL	44.4050 mL
5 mM	0.8881 mL	4.4405 mL	8.8810 mL
10 mM	0.4440 mL	2.2202 mL	4.4405 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.91%

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Data Sheet (242 KB) SDS (393 KB)

COA (247 KB) HNMR (231 KB) MS (265 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.4405 mL	22.2025 mL	44.4050 mL	111.0124 mL
	5 mM	0.8881 mL	4.4405 mL	8.8810 mL	22.2025 mL
	10 mM	0.4440 mL	2.2202 mL	4.4405 mL	11.1012 mL
	15 mM	0.2960 mL	1.4802 mL	2.9603 mL	7.4008 mL
	20 mM	0.2220 mL	1.1101 mL	2.2202 mL	5.5506 mL
	25 mM	0.1776 mL	0.8881 mL	1.7762 mL	4.4405 mL
	30 mM	0.1480 mL	0.7401 mL	1.4802 mL	3.7004 mL
	40 mM	0.1110 mL	0.5551 mL	1.1101 mL	2.7753 mL
	50 mM	0.0888 mL	0.4440 mL	0.8881 mL	2.2202 mL
	60 mM	0.0740 mL	0.3700 mL	0.7401 mL	1.8502 mL
	80 mM	0.0555 mL	0.2775 mL	0.5551 mL	1.3877 mL
	100 mM	0.0444 mL	0.2220 mL	0.4440 mL	1.1101 mL