2. PROTAC
  3. Ligands for Target Protein for PROTAC
  4. SMARCA-BD ligand 1 for PROTAC

SMARCA-BD ligand 1 for PROTAC is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.

For research use only. We do not sell to patients.

SMARCA-BD ligand 1 for PROTAC Chemical Structure

SMARCA-BD ligand 1 for PROTAC Chemical Structure

CAS No. : 1997319-92-2

Size Price Stock Quantity
5 mg USD 180 In-stock
10 mg USD 290 In-stock
25 mg USD 490 In-stock
50 mg USD 690 In-stock
100 mg USD 940 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of SMARCA-BD ligand 1 for PROTAC:

SMARCA-BD ligand 1 for PROTAC Related Antibodies

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1 Publications Citing Use of MCE SMARCA-BD ligand 1 for PROTAC

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Description

SMARCA-BD ligand 1 for PROTAC is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC[1].

IC50 & Target

SMARCA2[1]
Molecular Weight

271.32

Formula

C14H17N5O
CAS No.
Appearance

Solid

Color

Light yellow to light brown

SMILES

OC1=CC=CC=C1C2=NN=C(N)C(N3CCNCC3)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (122.84 mM; ultrasonic and adjust pH to 6 with 1 M HCL; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6857 mL 18.4284 mL 36.8568 mL
5 mM 0.7371 mL 3.6857 mL 7.3714 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6857 mL 18.4284 mL 36.8568 mL 92.1421 mL
5 mM 0.7371 mL 3.6857 mL 7.3714 mL 18.4284 mL
10 mM 0.3686 mL 1.8428 mL 3.6857 mL 9.2142 mL
15 mM 0.2457 mL 1.2286 mL 2.4571 mL 6.1428 mL
20 mM 0.1843 mL 0.9214 mL 1.8428 mL 4.6071 mL
25 mM 0.1474 mL 0.7371 mL 1.4743 mL 3.6857 mL
30 mM 0.1229 mL 0.6143 mL 1.2286 mL 3.0714 mL
40 mM 0.0921 mL 0.4607 mL 0.9214 mL 2.3036 mL
50 mM 0.0737 mL 0.3686 mL 0.7371 mL 1.8428 mL
60 mM 0.0614 mL 0.3071 mL 0.6143 mL 1.5357 mL
80 mM 0.0461 mL 0.2304 mL 0.4607 mL 1.1518 mL
100 mM 0.0369 mL 0.1843 mL 0.3686 mL 0.9214 mL
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SMARCA-BD ligand 1 for PROTAC Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SMARCA-BD ligand 1 for PROTAC1997319-92-2Ligands for Target Protein for PROTACTarget Protein-binding MoietyInhibitorinhibitorinhibit

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