2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Interleukin & Receptors
  5. IL-10 Receptor

IL-10 Receptor

Related Products

XLSX 4.18 KB

The interleukin 10 receptor (IL-10R) is a type II cytokine receptor consisting of a tetramer of 2 alpha and 2 beta subunits. The α subunit, also known as IL-10RI, is a ligand-binding subunit, while the β subunit, also known as IL-10RII, is a co-subunit required for signal transduction. IL-10 receptor expression is mainly characterized in cells of the hematopoietic spectrum, such as dendritic cells, B cells, T cells, NK cells, neutrophils, monocytes, and macrophages. When IL-10R binds to its ligand IL-10, it induces phosphorylation of Jak1 and Tyk2 and activates the transcription factor STAT3. activated STAT3 monomers dimerize and enter the nucleus to induce gene expression. IL-10R-mediated signaling pathways play an important role in immune tolerance, T cell and DC development, and B cell growth and differentiation[1][2].

Subscribe Now to the List of Recombinant Proteins

 
Cat. No. Product Name / Synonyms Species Source
  • HY-P74839
    IL-10R beta Protein, Human (HEK293, His-hFc)

    Interleukin-10 receptor subunit beta; IL-10RB; CRF2-4; IL-10R2; CDw210b

    		Human HEK293
    IL-10R beta protein is an IL10 cytokine surface receptor involved in IL10-mediated inflammation and immune regulation, as well as viral defense responses. IL-10R beta Protein, Human (HEK293, His-hFc) is expressed by HEK293 cells and with a His and -hFc tag at the C-terminus.
  • HY-P70692
    IL-10R alpha Protein, Human (HEK293, His)

    Interleukin-10 receptor subunit alpha; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; CDw210a; Interleukin-10 receptor subunit 1; IL-10R subunit 1; IL-10R1; CD210; IL10RA

    		Human HEK293
    IL-10R alpha protein is an IL10 cytokine surface receptor that is involved in IL10-mediated inflammation and immune regulation and inhibits the synthesis of pro-inflammatory cytokines. IL-10R alpha Protein, Human (HEK293, His) is expressed by HEK 293 cells and has a transmembrane region (V236-L256) with a 6*His tag at the C-terminus.
  • HY-P74837
    IL-10R beta Protein, Mouse (HEK293, His)

    Interleukin-10 receptor subunit beta; IL-10RB; CRF2-4; IL-10R2; CDw210b

    		Mouse HEK293
    IL-10R beta protein is an IL10 cytokine surface receptor involved in IL10-mediated inflammation and immune regulation, as well as viral defense responses. IL-10R beta Protein, Mouse (HEK293, His) is expressed by HEK 293 cells and has a transmembrane region (W223-Y251) with a His tag at the C-terminus.
  • HY-P700639
    IL-10R alpha Protein, Human (HEK293)

    Interleukin-10 receptor subunit alpha; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; CDw210a; Interleukin-10 receptor subunit 1; IL-10R subunit 1; IL-10R1; CD210; IL10RA

    		Human HEK293
    IL-10R alpha protein is an IL10 cytokine surface receptor that is involved in IL10-mediated inflammation and immune regulation and inhibits the synthesis of pro-inflammatory cytokines. IL-10R alpha Protein, Human (HEK293, His) is expressed by HEK 293 cells and has a transmembrane region (V236-L256) with a 6*His tag at the C-terminus.
  • HY-P72599
    IL-10R beta Protein, Human (HEK293, His)

    Interleukin-10 receptor subunit beta; IL-10RB; CRF2-4; IL-10R2; CDw210b

    		Human HEK293
    IL-10R beta protein is an IL10 cytokine surface receptor involved in IL10-mediated inflammation and immune regulation, as well as viral defense responses.IL-10R beta Protein, Human (HEK293, His) is expressed by HEK 293 cells and has a transmembrane region (W221-F242) with a 6*His tag at the C-terminus.
  • HY-P76987
    IL-10R alpha Protein, Rhesus Macaque (HEK293, Fc)

    Interleukin-10 receptor subunit alpha; IL-10RA; CDw210a; IL-10R1; CD210

    		Rhesus Macaque HEK293
    IL-10R alpha protein is an IL10 cytokine surface receptor that is involved in IL10-mediated inflammation and immune regulation and inhibits the synthesis of pro-inflammatory cytokines.IL-10R alpha Protein, Rhesus Macaque (HEK293, Fc) is expressed in HEK 293 cells and consists of 590 amino acids (M1-S590) with a -hFc tag at the C-terminus.
  • HY-P76988
    IL-10R alpha Protein, Rhesus Macaque (HEK293, His)

    Interleukin-10 receptor subunit alpha; IL-10RA; CDw210a; IL-10R1; CD210

    		Rhesus Macaque HEK293
    IL-10R alpha protein is an IL10 cytokine surface receptor that is involved in IL10-mediated inflammation and immune regulation and inhibits the synthesis of pro-inflammatory cytokines. IL-10R alpha Protein, Rhesus Macaque (HEK293, His) is expressed in HEK 293 cells and consists of 590 amino acids (M1-S590) with a His tag at the C-terminus.
  • HY-P78464
    IL-10R alpha Protein, Human (HEK293, His-Avi)

    IL-10RA; IL10RA; IL10R; IL-10R1; IL-10R subunit 1; CDw210a; HIL-10R; IBD28; IL-10 R alpha

    		Human HEK293
    IL-10R alpha protein is an IL10 cytokine surface receptor that is involved in IL10-mediated inflammation and immune regulation and inhibits the synthesis of pro-inflammatory cytokines. IL-10R alpha Protein, Human (HEK293, His-Avi) is expressed by HEK 293 cells and has a transmembrane region (V236-L256) with a His and Avi tag at the C-terminus.
  • HY-P700741
    IL-10R alpha Protein, Cynomolgus (HEK293, His)

    IL-10RA; IL10RA; IL10R; IL-10R1; IL-10R subunit 1; CDw210a; HIL-10R; IBD28; IL-10 R alpha

    		Cynomolgus HEK293
  • HY-P75825
    IL-10R alpha Protein, Mouse (HEK293, Fc)

    Interleukin-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; CDw210a; Interleukin-10 receptor subunit 1; IL-10R1; CD210; IL10RA

    		Mouse HEK293
    IL-10R alpha protein is an IL10 cytokine surface receptor that is involved in IL10-mediated inflammation and immune regulation and inhibits the synthesis of pro-inflammatory cytokines. IL-10R alpha Protein, Mouse (HEK293, Fc) is expressed by HEK 293cells with a hFc tag at the C-terminus.
  • HY-P76414
    IL-10R beta Protein, Rat (HEK293, Fc)

    Interleukin-10 receptor subunit beta; IL-10RB; CRF2-4; IL-10R2; CDw210b

    		Rat HEK293
    IL-10R beta protein is an IL10 cytokine surface receptor involved in IL10-mediated inflammation and immune regulation, as well as viral defense responses.IL-10R beta Protein, Rat (HEK293, Fc) is expressed by HEK 293 cells and consists of 351 amino acids (M1-V351) with a Fc tag at the C-terminus.
  • HY-P74838
    IL-10R beta Protein, Mouse (HEK293, hFc)

    Interleukin-10 receptor subunit beta; IL-10RB; CRF2-4; IL-10R2; CDw210b

    		Mouse HEK293
    IL-10R beta protein is an IL10 cytokine surface receptor involved in IL10-mediated inflammation and immune regulation, as well as viral defense responses. IL-10R beta Protein, Mouse (HEK293, hFc) is expressed by HEK 293 cells and has a transmembrane region (W223-Y251) with a hFc tag at the C-terminus.
Cat. No. Product Name Effect Purity