2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Interleukin & Receptors
  5. IL-11 Receptor

IL-11 Receptor

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IL-11 receptor is a type-I transmembrane protein, binding to interleukin 11. The IL-11 receptor comprises IL-11Rα and an incompletely characterized beta subunit[1]. IL-11 binds to IL-11 receptor and induces gp130 homodimerization, activates several intracellular signaling cascades, among them the Janus kinase/signal transducer and activator of transcription (Jak/STAT), the phosphoinositide 3-kinase (PI3K), and the mitogen-activated protein kinase (MAPK) pathway[2].

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Cat. No. Product Name / Synonyms Species Source
  • HY-P76416
    IL-11R alpha Protein, Human (HEK293, His)

    IL-11 R alpha; IL11R alpha; IL11RA; IL-11Ra; Il11ra2; NR1

    		Human HEK293
    IL-11R alpha (IL-11RA) is the IL-11 receptor subunit α and also acts as an agonist of IL-11. IL-11R alpha binds to IL6ST/gp130 on cell surfaces and induces signal transduction. IL-11R alpha activates Jak family of tyrosine kinases, JAK1, JAK2, and TYK2. IL-11R alpha induces proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. IL-11R alpha plays an important role in the progression and the differentiation of human gastric carcinomas. IL-11R alpha Protein, Human (HEK293, His) is a recombinant protein with a His label that consists of 341 amino acids (S23-V363) and is produced by HEK293 cells.
  • HY-P77400
    IL-11R alpha Protein, Rat (HEK293, His)

    IL-11 R alpha; IL11R alpha; IL11RA; IL-11Ra; Il11ra2; NR1

    		Rat HEK293
    IL-11R alpha (IL-11RA) is the IL-11 receptor subunit α and also acts as an agonist of IL-11. IL-11R alpha binds to IL6ST/gp130 on cell surfaces and induces signal transduction. IL-11R alpha activates Jak family of tyrosine kinases, JAK1, JAK2, and TYK2. IL-11R alpha induces proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. IL-11R alpha plays an important role in the progression and the differentiation of human gastric carcinomas. IL-11R alpha Protein, Rat (HEK293, His) is a recombinant protein with a His label that consists of 366 amino acids (M1-Q366) and is produced by HEK293 cells.
  • HY-P77398
    IL-11R alpha Protein, Canine (HEK293, Fc)

    IL-11 R alpha; IL11R alpha; IL11RA; IL-11Ra; Il11ra2; NR1

    		Canine HEK293
    IL-11R alpha (IL-11RA) is the IL-11 receptor subunit α and also acts as an agonist of IL-11. IL-11R alpha binds to IL6ST/gp130 on cell surfaces and induces signal transduction. IL-11R alpha activates Jak family of tyrosine kinases, JAK1, JAK2, and TYK2. IL-11R alpha induces proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. IL-11R alpha plays an important role in the progression and the differentiation of human gastric carcinomas. IL-11R alpha Protein, Canine (HEK293, Fc) is a recombinant protein with a Fc label produced by HEK293 cells.
  • HY-P70860
    IL-11R alpha Protein, Mouse (HEK293, His)

    IL-11 R alpha; IL11R alpha; IL11RA; IL-11Ra; Il11ra2; NR1

    		Mouse HEK293
    IL-11R alpha (IL-11RA) is the IL-11 receptor subunit α and also acts as an agonist of IL-11. IL-11R alpha binds to IL6ST/gp130 on cell surfaces and induces signal transduction. IL-11R alpha activates Jak family of tyrosine kinases, JAK1, JAK2, and TYK2. IL-11R alpha induces proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. IL-11R alpha plays an important role in the progression and the differentiation of human gastric carcinomas. IL-11R alpha Protein, Mouse (HEK293, His) is a recombinant protein with a His label that consists of 344 amino acids (S24-Q367) and is produced by HEK293 cells.
  • HY-P77397
    IL-11R alpha Protein, Canine (HEK293)

    IL-11 R alpha; IL11R alpha; IL11RA; IL-11Ra; Il11ra2; NR1

    		Canine HEK293
    IL-11R alpha (IL-11RA) is the IL-11 receptor subunit α and also acts as an agonist of IL-11. IL-11R alpha binds to IL6ST/gp130 on cell surfaces and induces signal transduction. IL-11R alpha activates Jak family of tyrosine kinases, JAK1, JAK2, and TYK2. IL-11R alpha induces proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. IL-11R alpha plays an important role in the progression and the differentiation of human gastric carcinomas. IL-11R alpha Protein, Canine (HEK293) is a recombinant protein produced by HEK293 cells.
  • HY-P77399
    IL-11R alpha Protein, Canine (HEK293, His)

    IL-11 R alpha; IL11R alpha; IL11RA; IL-11Ra; Il11ra2; NR1

    		Canine HEK293
    IL-11R alpha (IL-11RA) is the IL-11 receptor subunit α and also acts as an agonist of IL-11. IL-11R alpha binds to IL6ST/gp130 on cell surfaces and induces signal transduction. IL-11R alpha activates Jak family of tyrosine kinases, JAK1, JAK2, and TYK2. IL-11R alpha induces proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. IL-11R alpha plays an important role in the progression and the differentiation of human gastric carcinomas. IL-11R alpha Protein, Canine (HEK293, His) is a recombinant protein with a His label produced by HEK293 cells.
Cat. No. Product Name Effect Purity