1. Membrane Transporter/Ion Channel
  2. Proton Pump
  3. Protonstatin-1

Protonstatin-1 is a selective plasma membrane (PM) H+-ATPase inhibitor (IC50 of 3.9 μM) that inhibits auxin transport. Protonstatin-1 interacts with the PM H+-ATPase central loop and may thus impede the functions of the N- and/or P-domain to inhibit the pump activity.

For research use only. We do not sell to patients.

Protonstatin-1 Chemical Structure

Protonstatin-1 Chemical Structure

CAS No. : 521972-99-6

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Based on 1 publication(s) in Google Scholar

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Description

Protonstatin-1 is a selective plasma membrane (PM) H+-ATPase inhibitor (IC50 of 3.9 μM) that inhibits auxin transport. Protonstatin-1 interacts with the PM H+-ATPase central loop and may thus impede the functions of the N- and/or P-domain to inhibit the pump activity[1][2].

In Vitro

Protonstatin-1 (25 μM) decreases the inhibition of AHA2 activity in yeast strain RS72-AHA2, resulting in decreased yeast cell growth[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

211.26

Formula

C8H5NO2S2

CAS No.
SMILES

O=C1NC(S/C1=C\C2=CC=CO2)=S

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Protonstatin-1 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Protonstatin-1
Cat. No.:
HY-W317853
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