2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Pruvanserin

Pruvanserin  (Synonyms: EMD 281014 free acid; LY 2422347)

Cat. No.: HY-106246 Purity: 99.27%
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Pruvanserin (EMD 281014 free acid) is a selective 5-HT2A receptor antagonist. Pruvanserin alleviates tactile allodynia in diabetic rats. Pruvanserin can also be used for research of insomnia.

For research use only. We do not sell to patients.

Pruvanserin Chemical Structure

Pruvanserin Chemical Structure

CAS No. : 443144-26-1

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10 mg USD 470 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Pruvanserin:

Pruvanserin Related Antibodies

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5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

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Description

Pruvanserin (EMD 281014 free acid) is a selective 5-HT2A receptor antagonist. Pruvanserin alleviates tactile allodynia in diabetic rats. Pruvanserin can also be used for research of insomnia[1].

IC50 & Target[1]

5-HT2A Receptor

 

Molecular Weight

376.43

Formula

C22H21FN4O
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

N#CC1=CNC2=C1C=CC=C2C(N3CCN(CC3)CCC4=CC=C(C=C4)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Pruvanserin Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pruvanserin443144-26-1EMD 281014 LY 2422347EMD281014EMD-281014LY2422347LY 2422347LY-24223475-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptordiabeticinsomniaInhibitorinhibitorinhibit

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